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BUB3 Products

(Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))

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This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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Featured BUB3 Categories

BUB3 Antibodies

High quality antibodies with extensive validation data.

BUB3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended BUB3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (4)
Cat. No. ABIN604943
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC (p), ICC, IHC (fro)
Validations
  • (5)
Cat. No. ABIN3044239
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7160076
Quantity 100 μg
Datasheet Datasheet

Recommended BUB3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6227471
Quantity 96 tests
Datasheet Datasheet

Recommended BUB3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN1098754
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346989
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN2128225
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our BUB3 products

Jiang, Li, Yang, Hawke, Zheng, Xia, Aldape, Wei, Guo, Chen, Lu: "PKM2 regulates chromosome segregation and mitosis progression of tumor cells." in: Molecular cell, Vol. 53, Issue 1, pp. 75-87, (2014) (PubMed).

Morais da Silva, Moutinho-Santos, Sunkel: "A tumor suppressor role of the Bub3 spindle checkpoint protein after apoptosis inhibition." in: The Journal of cell biology, Vol. 201, Issue 3, pp. 385-93, (2013) (PubMed).

Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: "Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy." in: Journal of proteomics, Vol. 75, Issue 7, pp. 2236-51, (2012) (PubMed).

Warren, Brady, Johnston, Hanna, Hardwick, Spencer: "Distinct chromosome segregation roles for spindle checkpoint proteins." in: Molecular biology of the cell, Vol. 13, Issue 9, pp. 3029-41, (2002) (PubMed).

Kalitsis, Earle, Fowler, Choo: "Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis." in: Genes & development, Vol. 14, Issue 18, pp. 2277-82, (2000) (PubMed).

Martinez-Exposito, Kaplan, Copeland, Sorger: "Retention of the BUB3 checkpoint protein on lagging chromosomes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 15, pp. 8493-8, (1999) (PubMed).

Taylor, Ha, McKeon: "The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase." in: The Journal of cell biology, Vol. 142, Issue 1, pp. 1-11, (1998) (PubMed).

Roberts, Farr, Hoyt: "The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase." in: Molecular and cellular biology, Vol. 14, Issue 12, pp. 8282-91, (1994) (PubMed).

Synonyms and alternative names related to BUB3

BUB3, mitotic checkpoint protein (BUB3), BUB3 mitotic checkpoint protein (Bub3), BUB3 mitotic checkpoint protein L homeolog (bub3.L), Aa2-050, AU019800, AU021329, AU043350, AW146323, BUB3L, C78067, hBUB3, xbub3

Protein level used designations for BUB3

  • BUB3 budding uninhibited by benzimidazoles 3 homolog
  • budding uninhibited by benomyl
  • budding uninhibited by benzimidazoles 3 homolog
  • mitotic checkpoint component
  • mitotic checkpoint protein BUB3
  • WD repeat protein Bub3
  • WD repeat type I transmembrane protein A72.5
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