BUB1 Products
(Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))
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This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer. [provided by RefSeq, Jul 2008].
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Featured BUB1 Categories
BUB1 Antibodies
High quality antibodies with extensive validation data.
BUB1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BUB1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, PLA
Validations
- (5)
Cat. No.
ABIN513834
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (5)
Cat. No.
ABIN560107
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN5542587
Quantity
100 μL
Datasheet
Datasheet
Recommended BUB1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346981
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346983
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3131338
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our BUB1 products
: "Murine leukemia P388 vinorelbine-resistant cell lines are sensitive to vinflunine." in: Investigational new drugs, Vol. 26, Issue 4, pp. 319-30, (2008) (PubMed).: "Bub1: escapades in a cellular world." in: Cell cycle (Georgetown, Tex.), Vol. 6, Issue 14, pp. 1699-704, (2007) (PubMed).
: "Bub1 is essential for assembly of the functional inner centromere." in: The Journal of cell biology, Vol. 176, Issue 7, pp. 919-28, (2007) (PubMed).
: "Genome-scale RNAi profiling of cell division in human tissue culture cells." in: Nature cell biology, Vol. 9, Issue 12, pp. 1401-12, (2007) (PubMed).
: "Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1." in: Molecular biology of the cell, Vol. 17, Issue 8, pp. 3705-16, (2006) (PubMed).
: "TPPII promotes genetic instability by allowing the escape from apoptosis of cells with activated mitotic checkpoints." in: Biochemical and biophysical research communications, Vol. 346, Issue 2, pp. 415-25, (2006) (PubMed).
: "Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells." in: The Journal of cell biology, Vol. 175, Issue 1, pp. 41-53, (2006) (PubMed).
: "A dual role for Bub1 in the spindle checkpoint and chromosome congression." in: The EMBO journal, Vol. 24, Issue 8, pp. 1621-33, (2005) (PubMed).
: "Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20." in: Journal of cell science, Vol. 118, Issue Pt 16, pp. 3639-52, (2005) (PubMed).
: "Phosphorylation of Cdc20 by Bub1 provides a catalytic mechanism for APC/C inhibition by the spindle checkpoint." in: Molecular cell, Vol. 16, Issue 3, pp. 387-97, (2004) (PubMed).
Synonyms and alternative names related to BUB1
BUB1 mitotic checkpoint serine/threonine kinase (BUB1), BUB1 mitotic checkpoint serine/threonine kinase (bub1), BUB1 mitotic checkpoint serine/threonine kinase (Bub1), BUB1, mitotic checkpoint serine/threonine kinase (Bub1), AL022991, bub1a, BUB1A, Bub1a, bub1l, BUB1L, C80208, D2Xrf87, hbub1, hBUB1, xbub1Protein level used designations for BUB1
- BUB1 budding uninhibited by benzimidazoles 1 homolog
- mitotic checkpoint serine/threonine-protein kinase BUB1
- budding uninhibited by benzimidazoles 1
- budding uninhibited by benzimidazoles 1 homolog
- mitotic spindle checkpoint kinase
- putative serine/threonine-protein kinase
- mBUB1
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