BTK Products
(Bruton Agammaglobulinemia tyrosine Kinase (BTK))
Categories
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq, Nov 2008].
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Featured BTK Categories
BTK Antibodies
High quality antibodies with extensive validation data.
BTK ELISA Kits
Reliable ELISA kits for a wide range of species.
BTK Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BTK Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN3022171
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7265950
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (5)
Cat. No.
ABIN3030207
Quantity
0.4 mL
Datasheet
Datasheet
Recommended BTK ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
Cat. No.
ABIN1981713
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965243
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965242
Quantity
96 tests
Datasheet
Datasheet
Recommended BTK Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7491289
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346956
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346958
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our BTK products
: "Repositioning Flubendazole for Spinal Cord Injury." in: Journal of neurotrauma, (2019) (PubMed).: "Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 192-200, (2017) (PubMed).
: "X-linked agammaglobulinemia associated with B-precursor acute lymphoblastic leukemia." in: Journal of clinical immunology, Vol. 35, Issue 2, pp. 108-11, (2015) (PubMed).
: "Amplification of IL-21 signalling pathway through Bruton's tyrosine kinase in human B cell activation." in: Rheumatology (Oxford, England), Vol. 54, Issue 8, pp. 1488-97, (2015) (PubMed).
: "Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor." in: Cell death & disease, Vol. 5, pp. e1409, (2014) (PubMed).
: "A novel Bruton's tyrosine kinase inhibitor CC-292 in combination with the proteasome inhibitor carfilzomib impacts the bone microenvironment in a multiple myeloma model with resultant antimyeloma ..." in: Leukemia, Vol. 28, Issue 9, pp. 1892-901, (2014) (PubMed).
: "Synergistic growth-inhibitory effects of ponatinib and midostaurin (PKC412) on neoplastic mast cells carrying KIT D816V." in: Haematologica, Vol. 98, Issue 9, pp. 1450-7, (2013) (PubMed).
: "Bruton's tyrosine kinase mediates FcγRIIa/Toll-like receptor-4 receptor crosstalk in human neutrophils." in: American journal of respiratory cell and molecular biology, Vol. 48, Issue 2, pp. 240-9, (2013) (PubMed).
: "Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling." in: Immunological reviews, Vol. 203, pp. 200-15, (2005) (PubMed).
: "Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice." in: Cancer research, Vol. 64, Issue 20, pp. 7183-90, (2004) (PubMed).
Synonyms and alternative names related to BTK
Bruton tyrosine kinase (BTK), Bruton agammaglobulinemia tyrosine kinase (btk), Bruton tyrosine kinase (btk), Bruton agammaglobulinemia tyrosine kinase (Btk), Bruton tyrosine kinase (Btk), agmx1, AGMX1, AI528679, AT, atk, ATK, bpk, BPK, BTK, imd1, IMD1, psctk1, PSCTK1, xid, xla, XLAProtein level used designations for BTK
- Bruton agammaglobulinemia tyrosine kinase
- B-cell progenitor kinase
- agammaglobulinaemia tyrosine kinase
- dominant-negative kinase-deficient Brutons tyrosine kinase
- tyrosine-protein kinase BTK
- tyrosine-protein kinase BTK isoform (lacking exon 14)
- ATK
- BPK
- Bruton's tyrosine kinase
- Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB)
- X-linked immune deficiency
- agammaglobulinemia tyrosine kinase
- bruton tyrosine kinase
- kinase EMB
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