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BSP Products

(Bone Sialoprotein (BSP))
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008].

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Featured BSP Categories

BSP Antibodies

High quality antibodies with extensive validation data.

BSP ELISA Kits

Reliable ELISA kits for a wide range of species.

BSP Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended BSP Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, ICC, RIA, IHC (fro)
Validations
  • (2)
  • (3)
Cat. No. ABIN109798
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (1)
Cat. No. ABIN7073219
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, ICC, RIA
Validations
  • (1)
Cat. No. ABIN109784
Quantity 100 μg
Datasheet Datasheet

Recommended BSP ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6954157
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6975241
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965213
Quantity 96 tests
Datasheet Datasheet

Recommended BSP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7411705
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393211
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6120428
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our BSP products

Zepp, Kovacheva, Altankhuyag, Westphal, Berger, Gather, Hilbig, Neuhaus, Hänsch, Armbruster, Berger: "IDK1 is a rat monoclonal antibody against hypoglycosylated bone sialoprotein with application as biomarker and therapeutic agent in breast cancer skeletal metastasis." in: The journal of pathology. Clinical research, Vol. 4, Issue 1, pp. 55-68, (2018) (PubMed).

Mazur, Wypasek, Gawęda, Sobczyk, Kapusta, Natorska, Malinowski, Tarasiuk, Bochenek, Wroński, Chmielewska, Kapelak, Undas: "Stenotic Bicuspid and Tricuspid Aortic Valves - Micro-Computed Tomography and Biological Indices of Calcification." in: Circulation journal : official journal of the Japanese Circulation Society, Vol. 81, Issue 7, pp. 1043-1050, (2017) (PubMed).

Pu, Wu, Lu, Hu, Li, Wu, Tang: "Adiponectin Promotes Human Jaw Bone Marrow Stem Cell Osteogenesis." in: Journal of dental research, Vol. 95, Issue 7, pp. 769-75, (2016) (PubMed).

Manaka, Tanabe, Kariya, Naito, Takayama, Nagao, Liu, Ito, Maeno, Suzuki, Miyazaki: "Low-intensity pulsed ultrasound-induced ATP increases bone formation via the P2X7 receptor in osteoblast-like MC3T3-E1 cells." in: FEBS letters, Vol. 589, Issue 3, pp. 310-8, (2015) (PubMed).

Hoffmann, Feliciano, Martin, de Wild, Wendt: "Novel Perfused Compression Bioreactor System as an in vitro Model to Investigate Fracture Healing." in: Frontiers in bioengineering and biotechnology, Vol. 3, pp. 10, (2015) (PubMed).

Koseki, Kaku, Kawata, Kojima, Sumi, Shikata, Motokawa, Fujita, Ohtani, Tanne: "Cryopreservation of osteoblasts by use of a programmed freezer with a magnetic field." in: Cryo letters, Vol. 34, Issue 1, pp. 10-9, (2013) (PubMed).

Synonyms and alternative names related to BSP

integrin-binding sialoprotein (Ibsp), integrin binding sialoprotein (IBSP), integrin binding sialoprotein (Ibsp), BNSP, Bsp, BSP, BSP-II, Bsp2, BSP II, BSPII, SP-II

Protein level used designations for BSP

  • BSP II
  • bone sialoprotein 2
  • bone sialoprotein II
  • cell-binding sialoprotein
  • integrin binding sialoprotein
  • integrin-binding sialoprotein
  • integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II)
  • Bone sialoprotein 2
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