BRSK2 Products
(BR serine/threonine Kinase 2 (BRSK2))
Categories
Serine/threonine-protein kinase that plays a key role in polarization of neurons. Phosphorylates MAPT/TAU and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Ser-554'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 activity in polarized neurons.
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Featured BRSK2 Categories
BRSK2 Antibodies
High quality antibodies with extensive validation data.
BRSK2 ELISA Kits
Reliable ELISA kits for a wide range of species.
BRSK2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BRSK2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN391285
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF, FACS
Validations
- (2)
Cat. No.
ABIN185503
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7254727
Quantity
200 μL
Datasheet
Datasheet
Recommended BRSK2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1157192
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1157193
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1157194
Quantity
96 tests
Datasheet
Datasheet
Recommended BRSK2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346889
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5508832
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3090447
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our BRSK2 products
: "BR serine/threonine kinase 2: a new autoantigen in paraneoplastic limbic encephalitis." in: Journal of neuroimmunology, Vol. 170, Issue 1-2, pp. 186-90, (2005) (PubMed).: "Mammalian SAD kinases are required for neuronal polarization." in: Science (New York, N.Y.), Vol. 307, Issue 5711, pp. 929-32, (2005) (PubMed).
: "LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1." in: The EMBO journal, Vol. 23, Issue 4, pp. 833-43, (2004) (PubMed).
: "Human SAD1 kinase is involved in UV-induced DNA damage checkpoint function." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31164-70, (2004) (PubMed).
: "The protein kinase complement of the human genome." in: Science (New York, N.Y.), Vol. 298, Issue 5600, pp. 1912-34, (2002) (PubMed).
Synonyms and alternative names related to BRSK2
BR serine/threonine kinase 2 (BRSK2), BR serine/threonine kinase 2 (Brsk2), 4833424K13Rik, BRSK2, C11orf7, PEN11B, SAD-A, SAD1, SADA, STK29Protein level used designations for BRSK2
- BR serine/threonine-protein kinase 2
- brain-selective kinase 2
- brain-specific serine/threonine-protein kinase 2
- protein kinase SAD1B
- serine/threonine-protein kinase 29
- serine/threonine-protein kinase BRSK2
- serine/threonine-protein kinase SAD-A
- BR serine/threonine kinase 2
- BR serine/threonine-protein kinase 2-like
- brain serine/threonine kinase 2
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