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BRSK1 Proteins

(BR Serine/threonine Kinase 1 (BRSK1))
Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, TUBG1, TUBG2 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Ser-573'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 activity in polarized neurons. Also acts as a positive regulator of centrosome duplication by mediating phosphorylation of gamma-tubulin (TUBG1 and TUBG2) at 'Ser-131', leading to translocation of gamma-tubulin and its associated proteins to the centrosome. Involved in the UV- induced DNA damage checkpoint response, probably by inhibiting CDK1 activity through phosphorylation and activation of WEE1, and inhibition of CDC25B and CDC25C (By similarity). In neurons, localizes to synaptic vesicles and plays a role in neurotransmitter release, possibly by phosphorylating RIMS1.
BRSK1 Protein (AA 289-380) (GST tag) BRSK1 Protein (AA 289-380) (GST tag) BRSK1 Protein (AA 289-380) (GST tag) (ABIN1346887)

BRSK1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

BRSK1 Protein (GST tag) (ABIN5509205)

BRSK1 Origin: Mouse Host: Insect Cells Recombinant 70 % - 90 % Func Active

BRSK1 Protein (AA 1-778) (Strep Tag) (ABIN3090446)

BRSK1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

BRSK1 Proteins by Origin

Find BRSK1 Proteins for a variety of species such as anti-Human BRSK1, anti-Mouse BRSK1, anti-Rat BRSK1. The species listed below are among those available. Click on a link to go to the corresponding products.

BRSK1 Proteins by Source

Here you will find BRSK1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

BRSK1 Proteins by Protein Type

Here you can find BRSK1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

BRSK1 Proteins by Application

Find BRSK1 Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

BRSK1 Proteins by Biological Activity

Find BRSK1 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular BRSK1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346887
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
Cat. No. ABIN5509205
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3090446
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3135216
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1670475
Quantity 1 mg
Datasheet Datasheet

Aliases for BRSK1 Proteins

BR serine/threonine kinase 1 (BRSK1) Proteins
BR serine/threonine kinase 1 (Brsk1) Proteins
BRSK1 Proteins
Gm1100 Proteins
hSAD1 Proteins
RGD1563268 Proteins
SAD-B Proteins
Sad-b Proteins
SADB Proteins
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