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BRP44L Products

(Brain Protein 44-Like (BRP44L))
The protein encoded by this gene is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene. [provided by RefSeq, Aug 2012].

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Featured BRP44L Categories

BRP44L Antibodies

High quality antibodies with extensive validation data.

BRP44L ELISA Kits

Reliable ELISA kits for a wide range of species.

BRP44L Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended BRP44L Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6258687
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7188565
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Human, Monkey, Mouse, Rat
Application WB, IHC, IF, IC
Validations
  • (3)
Cat. No. ABIN7300998
Quantity 100 μL
Datasheet Datasheet

Recommended BRP44L ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960723
Quantity 96 tests
Datasheet Datasheet

Recommended BRP44L Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN6237670
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2715336
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our BRP44L products

Kim, Yu, Chen, Xu, Wu, Todorova, Tang, Feng, Jiang, He, Chen, Fu, Xu: "Wild-Type p53 Promotes Cancer Metabolic Switch by Inducing PUMA-Dependent Suppression of Oxidative Phosphorylation." in: Cancer cell, Vol. 35, Issue 2, pp. 191-203.e8, (2019) (PubMed).

Li, Ji, Han, Li, Fan, Li, Zhong, Cao, Zhao, Zhang, Wen, Goscinski, Nesland, Suo: "MPC1 and MPC2 expressions are associated with favorable clinical outcomes in prostate cancer." in: BMC cancer, Vol. 16, Issue 1, pp. 894, (2016) (PubMed).

Konstantakou, Voutsinas, Velentzas, Basogianni, Paronis, Balafas, Kostomitsopoulos, Syrigos, Anastasiadou, Stravopodis: "3-BrPA eliminates human bladder cancer cells with highly oncogenic signatures via engagement of specific death programs and perturbation of multiple signaling and metabolic determinants." in: Molecular cancer, Vol. 14, pp. 135, (2015) (PubMed).

Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).

Li, Han, Li, Kan, Fan, Li, Ji, Zhao, Zhang, Grigalavicius, Berge, Goscinski, Nesland, Suo: "Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells." in: Oncotarget, Vol. 8, Issue 28, pp. 46363-46380 (PubMed).

Synonyms and alternative names related to BRP44L

mitochondrial pyruvate carrier 1 (mpc1), mitochondrial pyruvate carrier 1 S homeolog (mpc1.S), uncharacterized protein (LOC542696), mitochondrial pyruvate carrier 1 (MPC1), mitochondrial pyruvate carrier 1 L homeolog (mpc1.L), brain protein 44-like (LOC100164048), brain protein 44-like (LOC100167201), mitochondrial pyruvate carrier 1 (Mpc1), 0610006G08Rik, 3830411I18Rik, brp44l, BRP44L, Brp44l, brp44la, brp44lb, CGI-129, dJ68L15.3, MGC64469, MGC90013, MPC1, MPYCD

Protein level used designations for BRP44L

  • brain protein 44-like
  • brain protein 44-like protein a
  • brain protein 44-like protein b
  • brain protein 44-like protein
  • putative brain protein 44-like variant 2
  • mitochondrial pyruvate carrier 1
  • HSPC040 protein
  • apoptosis-regulating basic protein
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