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BRIP1 Products

(BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))

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The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations. [provided by RefSeq, Jul 2008].

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Featured BRIP1 Categories

BRIP1 Antibodies

High quality antibodies with extensive validation data.

BRIP1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended BRIP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, FACS
Validations
  • (6)
Cat. No. ABIN7193527
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN2170674
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF, ICC
Validations
  • (3)
Cat. No. ABIN2857051
Quantity 100 μL
Datasheet Datasheet

Recommended BRIP1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1132971
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1132973
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1132972
Quantity 96 tests
Datasheet Datasheet

Recommended BRIP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122030
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092530
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3135242
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our BRIP1 products

Popp, Punekar, Telford, Stivaros, Chandler, Minnis, Castleton, Higham, Hopewell, Gareth Evans, Raams, Theil, Meyer, Schindler: "Fanconi anemia with sun-sensitivity caused by a Xeroderma pigmentosum-associated missense mutation in XPF." in: BMC medical genetics, Vol. 19, Issue 1, pp. 7, (2018) (PubMed).

Kim, Liu, Oberly, Freire, Smolka: "ATR-mediated proteome remodeling is a major determinant of homologous recombination capacity in cancer cells." in: Nucleic acids research, Vol. 46, Issue 16, pp. 8311-8325, (2018) (PubMed).

Bermudez-Hernandez, Keegan, Whelan, Reid, Zagelbaum, Yin, Ma, Rothenberg, Fenyö: "A Method for Quantifying Molecular Interactions Using Stochastic Modelling and Super-Resolution Microscopy." in: Scientific reports, Vol. 7, Issue 1, pp. 14882, (2017) (PubMed).

Romick-Rosendale, Hoskins, Privette Vinnedge, Foglesong, Brusadelli, Potter, Komurov, Brugmann, Lambert, Kimple, Virts, Hanenberg, Gillison, Wells: "Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 8, pp. 2062-73, (2016) (PubMed).

Sun, Brieño-Enríquez, Cornelius, Modzelewski, Maley, Campbell-Peterson, Holloway, Cohen: "FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice." in: Chromosoma, Vol. 125, Issue 2, pp. 237-52, (2016) (PubMed).

Aarts, Bajrami, Herrera-Abreu, Elliott, Brough, Ashworth, Lord, Turner: "Functional Genetic Screen Identifies Increased Sensitivity to WEE1 Inhibition in Cells with Defects in Fanconi Anemia and HR Pathways." in: Molecular cancer therapeutics, Vol. 14, Issue 4, pp. 865-76, (2015) (PubMed).

Knies, Schuster, Ameziane, Rooimans, Bettecken, de Winter, Schindler: "Genotyping of fanconi anemia patients by whole exome sequencing: advantages and challenges." in: PLoS ONE, Vol. 7, Issue 12, pp. e52648, (2013) (PubMed).

Nakanishi, Kitao, Fujinaka, Yamashita, Iimori, Tokunaga, Yamashita, Morita, Kakeji, Maehara: "FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer." in: Annals of surgical oncology, Vol. 19, Issue 11, pp. 3627-35, (2012) (PubMed).

Sakasai, Sakai, Iimori, Kiyonari, Matsuoka, Kakeji, Kitao, Maehara: "CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 17, Issue 12, pp. 962-70, (2012) (PubMed).

Vaz, Hanenberg, Schuster, Barker, Wiek, Erven, Neveling, Endt, Kesterton, Autore, Fraternali, Freund, Hartmann, Grimwade, Roberts, Schaal, Mohammed, Rahman, Schindler, Mathew: "Mutation of the RAD51C gene in a Fanconi anemia-like disorder." in: Nature genetics, Vol. 42, Issue 5, pp. 406-9, (2010) (PubMed).

Synonyms and alternative names related to BRIP1

BRCA1 interacting protein C-terminal helicase 1 (Brip1), BRCA1 interacting protein C-terminal helicase 1 L homeolog (brip1.L), BRCA1 interacting protein C-terminal helicase 1 (BRIP1), BRCA1 interacting protein C-terminal helicase 1 (brip1), 3110009N10Rik, 8030460J03Rik, BACH1, Bach1, BRIP1, FACJ, fancj, FANCJ, Fancj, MGC68622, OF, si:ch211-158l18.1

Protein level used designations for BRIP1

  • BRCA1 interacting protein C-terminal helicase 1
  • fanconi anemia group J protein
  • Fanconi anemia J
  • complementation group J
  • Fanconi anemia group J protein-like
  • ATP-dependent RNA helicase BRIP1
  • BRCA1-associated C-terminal helicase 1
  • BRCA1-binding helicase-like protein BACH1
  • BRCA1/BRCA2-associated helicase 1
  • Fanconi anemia group J protein
  • Fanconi anemia group J protein homolog
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