Bone Morphogenetic Protein Receptor 1A Products
(Bone Morphogenetic Protein Receptor 1A (BMPR1A))
Categories
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008].
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Featured Bone Morphogenetic Protein Receptor 1A Categories
Bone Morphogenetic Protein Receptor 1A Antibodies
High quality antibodies with extensive validation data.
Bone Morphogenetic Protein Receptor 1A ELISA Kits
Reliable ELISA kits for a wide range of species.
Bone Morphogenetic Protein Receptor 1A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Bone Morphogenetic Protein Receptor 1A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (2)
- (7)
Cat. No.
ABIN1724745
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, FACS, IHC (p)
Validations
- (5)
Cat. No.
ABIN687547
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
- (4)
Cat. No.
ABIN388732
Quantity
400 μL
Datasheet
Datasheet
Recommended Bone Morphogenetic Protein Receptor 1A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965211
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965210
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954153
Quantity
96 tests
Datasheet
Datasheet
Recommended Bone Morphogenetic Protein Receptor 1A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
Cat. No.
ABIN7320751
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7491355
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346780
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our Bone Morphogenetic Protein Receptor 1A products
: "A new signaling cascade linking BMP4, BMPR1A, ΔNp73 and NANOG impacts on stem-like human cell properties and patient outcome. ..." in: Cell death & disease, Vol. 9, Issue 10, pp. 1011, (2018) (PubMed).: "Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewal." in: Cell death & disease, Vol. 9, Issue 9, pp. 927, (2018) (PubMed).
: "BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5." in: PLoS ONE, Vol. 12, Issue 5, pp. e0177188, (2017) (PubMed).
: "Targeted disruption of BMP signaling through type IA receptor (BMPR1A) in osteocyte suppresses SOST and RANKL, leading to dramatic increase in bone mass, bone mineral density and mechanical strength." in: Bone, Vol. 91, pp. 53-63, (2017) (PubMed).
: "MicroRNA-195-5p Regulates Osteogenic Differentiation of Periodontal Ligament Cells Under Mechanical Loading." in: Journal of cellular physiology, Vol. 232, Issue 12, pp. 3762-3774, (2017) (PubMed).
: "The combined mechanism of bone morphogenetic protein- and calcium phosphate-induced skeletal tissue formation by human periosteum derived cells." in: European cells & materials, Vol. 31, pp. 11-25, (2016) (PubMed).
: "Augmented BMP signaling in the neural crest inhibits nasal cartilage morphogenesis by inducing p53-mediated apoptosis." in: Development (Cambridge, England), Vol. 142, Issue 7, pp. 1357-67, (2015) (PubMed).
: "The BMP Pathway Participates in Human Naive CD4+ T Cell Activation and Homeostasis." in: PLoS ONE, Vol. 10, Issue 6, pp. e0131453, (2015) (PubMed).
: "Optimal effector functions in human natural killer cells rely upon autocrine bone morphogenetic protein signaling." in: Cancer research, Vol. 74, Issue 18, pp. 5019-5031, (2015) (PubMed).
: "BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells." in: Molecular cancer research : MCR, Vol. 12, Issue 2, pp. 283-94, (2014) (PubMed).
Synonyms and alternative names related to Bone Morphogenetic Protein Receptor 1A
bone morphogenetic protein receptor type 1A (BMPR1A), bone morphogenetic protein receptor, type 1A (Bmpr1a), bone morphogenetic protein receptor type 1A (Bmpr1a), bone morphogenetic protein receptor type 1A (bmpr1a), bone morphogenetic protein receptor type 1A S homeolog (bmpr1a.S), bone morphogenetic protein receptor, type IAa (bmpr1aa), bone morphogenetic protein receptor, type IAb (bmpr1ab), 10q23del, 1110037I22Rik, ACVRLK3, acvrlk3, alk-3, ALK3, alk3, alk3tr, AU045487, Bmpr, BMPR-1, BMPR-IA, BMPR1A, bmpr1a, BR1a, BRK-1, CD292, cd292, SKR5, skr5, wu:fe05b06, wu:fe06e10, zgc:92227, zgc:136731Protein level used designations for Bone Morphogenetic Protein Receptor 1A
- ALK-3
- BMP type-1A receptor
- BMPR-1A
- activin A receptor, type II-like kinase 3
- activin receptor-like kinase 3
- bone morphogenetic protein receptor type-1A
- serine/threonine-protein kinase receptor R5
- BMP-2/BMP-4 receptor
- SKR5
- bone morphogenetic protein 4 receptor
- bone morphogenetic protein receptor, type 1A
- BMP receptor 1
- bone morphogenic protein receptor 1
- protein kinase
- bone morphogenetic protein receptor IA
- bone morphogenetic protein receptor, type IA
- bone morphogenetic protein receptor type-1A-like
- BMP receptor
- bone morphogenetic protein receptor type IA
- alk3a
- bone morphogenetic protein receptor, type 1a
- bone morphogenetic protein receptor, type 1aa
- alk3b
- bone morphogenetic protein receptor, type 1ab
- bone morphogenetic protein receptor, type IA,b
- bone morphogenetic protein receptor, type IAb
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