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BNIP3L/NIX Products

(BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

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This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2. [provided by RefSeq, Mar 2011].

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Featured BNIP3L/NIX Categories

BNIP3L/NIX Antibodies

High quality antibodies with extensive validation data.

BNIP3L/NIX ELISA Kits

Reliable ELISA kits for a wide range of species.

BNIP3L/NIX Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended BNIP3L/NIX Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, FACS, IHC (p)
Validations
  • (4)
Cat. No. ABIN655731
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
  • (3)
Cat. No. ABIN560088
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, WB, IF
Validations
  • (4)
Cat. No. ABIN6137622
Quantity 100 μL
Datasheet Datasheet

Recommended BNIP3L/NIX ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965140
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965141
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951385
Quantity 96 tests
Datasheet Datasheet

Recommended BNIP3L/NIX Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121990
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346802
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7317369
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our BNIP3L/NIX products

Vo, Smith, Nicholas, Choi: "Activation of NIX-mediated mitophagy by an interferon regulatory factor homologue of human herpesvirus." in: Nature communications, Vol. 10, Issue 1, pp. 3203, (2019) (PubMed).

Li, Zhang, Zhuang, Chen, Chen, Tian, Wu, Li, Wang, Zhang, Chen, Li, Zhao, Sui, Hu, Feng: "MicroRNA-137 is a novel hypoxia-responsive microRNA that inhibits mitophagy via regulation of two mitophagy receptors FUNDC1 and NIX." in: The Journal of biological chemistry, Vol. 289, Issue 15, pp. 10691-701, (2014) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Nakamura, Kitamura, Shinogi, Yoshida, Goda, Murai, Kamino, Arakawa: "BNIP3 and NIX mediate Mieap-induced accumulation of lysosomal proteins within mitochondria." in: PLoS ONE, Vol. 7, Issue 1, pp. e30767, (2012) (PubMed).

Miyamoto, Kitamura, Ono, Nakamura, Yoshida, Kamino, Murai, Yamada, Arakawa: "Identification of 14-3-3? as a Mieap-interacting protein and its role in mitochondrial quality control." in: Scientific reports, Vol. 2, pp. 379, (2012) (PubMed).

Zhang, Randall, Loyd, Dorsey, Kundu, Cleveland, Ney: "Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation." in: Blood, Vol. 114, Issue 1, pp. 157-64, (2009) (PubMed).

Qiu, Jiang, Xiang: "A comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursors." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 13, pp. 3392-403, (2008) (PubMed).

Marusyk, Wheeler, Mathews, DeGregori: "p53 mediates senescence-like arrest induced by chronic replicational stress." in: Molecular and cellular biology, Vol. 27, Issue 15, pp. 5336-51, (2007) (PubMed).

Passer, Nancy-Portebois, Amzallag, Prieur, Cans, Roborel de Climens, Fiucci, Bouvard, Tuynder, Susini, Morchoisne, Crible, Lespagnol, Dausset, Oren, Amson, Telerman: "The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 5, pp. 2284-9, (2003) (PubMed).

Aerbajinai, Giattina, Lee, Raffeld, Miller: "The proapoptotic factor Nix is coexpressed with Bcl-xL during terminal erythroid differentiation." in: Blood, Vol. 102, Issue 2, pp. 712-7, (2003) (PubMed).

Synonyms and alternative names related to BNIP3L/NIX

BCL2 interacting protein 3 like (BNIP3L), BCL2 interacting protein 3 (BNIP3), BCL2 interacting protein 3 like (Bnip3l), BCL2/adenovirus E1B interacting protein 3 (Bnip3), BCL2/adenovirus E1B interacting protein 3-like (Bnip3l), BCL2/adenovirus E1B interacting protein 3-like b (bnip3lb), BCL2/adenovirus E1B interacting protein 3-like a (bnip3la), BNIP3a, bnip3l, bnip3l2, C86132, D14Ertd719e, NIP3, Nip3, nip3, Nip3L, NIX, Nix, wu:fb52b03, wu:fc02h04, zgc:110478

Protein level used designations for BNIP3L/NIX

  • BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
  • BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A
  • BCL2/adenovirus E1B 19-kd protein-interacting protein 3a
  • NIP3-like protein X
  • NIP3L
  • adenovirus E1B19k-binding protein B5
  • BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
  • BCL2/adenovirus E1B 19 kDa-interacting protein 3-like
  • BCL2/adenovirus E1B 19 kDa-interacting protein 1, NIP3
  • BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP3
  • BCL2/adenovirus E1B interacting protein 1, NIP3
  • BCL2/adenovirus E1B 19kDa-interacting protein 3-like
  • BCL2/adenovirus E1B 19kD-interacting protein 3-like
  • BCL2/adenovirus E1B interacting protein 3-like b
  • BCL2/adenovirus E1b 19 kDa interacting protein 3a
  • nip3a
  • BCL2/adenovirus E1B interacting protein 3-like, 2
  • Nix
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