BMX Products
(BMX Non-Receptor Tyrosine Kinase (BMX))
Categories
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
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Featured BMX Categories
BMX Antibodies
High quality antibodies with extensive validation data.
BMX ELISA Kits
Reliable ELISA kits for a wide range of species.
BMX Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BMX Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (4)
Cat. No.
ABIN7443482
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6261616
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF
Validations
- (3)
Cat. No.
ABIN7184420
Quantity
100 μL
Datasheet
Datasheet
Recommended BMX ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965180
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954117
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380344
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended BMX Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346793
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN2715316
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Insect Cells
Validations
Cat. No.
ABIN5509204
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our BMX products
: "BMX Negatively Regulates BAK Function, Thereby Increasing Apoptotic Resistance to Chemotherapeutic Drugs." in: Cancer research, Vol. 75, Issue 7, pp. 1345-55, (2015) (PubMed).: "Estradiol modulates tumor necrosis factor-induced endothelial inflammation: role of tumor necrosis factor receptor 2." in: Journal of vascular research, Vol. 50, Issue 1, pp. 21-34, (2012) (PubMed).
: "The tyrosine kinase BMX is an essential mediator of inflammatory arthritis in a kinase-independent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 10, pp. 6014-23, (2011) (PubMed).
: "Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkapp}B activity." in: Blood, Vol. 111, Issue 4, pp. 1781-8, (2008) (PubMed).
: "Bone marrow X kinase-mediated signal transduction in irradiated vascular endothelium." in: Cancer research, Vol. 68, Issue 8, pp. 2861-9, (2008) (PubMed).
: "A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling." in: Nature cell biology, Vol. 7, Issue 8, pp. 797-807, (2005) (PubMed).
: "Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases." in: Biochimica et biophysica acta, Vol. 1645, Issue 2, pp. 123-32, (2003) (PubMed).
: "Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx." in: The Journal of biological chemistry, Vol. 277, Issue 11, pp. 9351-7, (2002) (PubMed).
: "Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1. A possible role of ETK in regulation of vesicle trafficking." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 30219-26, (2002) (PubMed).
: "Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: role in endothelial cell migration and angiogenesis." in: Molecular and cellular biology, Vol. 22, Issue 21, pp. 7512-23, (2002) (PubMed).
Synonyms and alternative names related to BMX
BMX non-receptor tyrosine kinase (BMX), BMX non-receptor tyrosine kinase (bmx), BMX non-receptor tyrosine kinase (Bmx), BMX, ETK, Etk, Etk/Bmx, PSCTK2, PSCTK3, RGD1565643, Tyro8Protein level used designations for BMX
- BMX non-receptor tyrosine kinase
- cytoplasmic tyrosine-protein kinase BMX-like
- BTK-like on X chromosome
- Etk/Bmx cytosolic tyrosine kinase
- NTK38 tyrosine kinase
- bone marrow tyrosine kinase gene in chromosome X protein
- cytoplasmic tyrosine-protein kinase BMX
- epithelial and endothelial tyrosine kinase
- TYRO8 protein tyrosine kinase 8
- bone marrow tyrosine kinase gene in chromosome X protein homolog
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