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BMI1 Polycomb Ring Finger Oncogene Products

(BMI1 Polycomb Ring Finger Oncogene (BMI1))

Categories

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2 (By similarity).

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Featured BMI1 Polycomb Ring Finger Oncogene Categories

BMI1 Polycomb Ring Finger Oncogene Antibodies

High quality antibodies with extensive validation data.

BMI1 Polycomb Ring Finger Oncogene ELISA Kits

Reliable ELISA kits for a wide range of species.

BMI1 Polycomb Ring Finger Oncogene Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended BMI1 Polycomb Ring Finger Oncogene Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IF, IHC (p), FACS
Validations
  • (3)
  • (7)
Cat. No. ABIN652702
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, ICC, FACS
Validations
  • (2)
  • (7)
Cat. No. ABIN968985
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IF, StM
Validations
  • (7)
Cat. No. ABIN6940582
Quantity 100 μg
Datasheet Datasheet

Recommended BMI1 Polycomb Ring Finger Oncogene ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6975046
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965176
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954110
Quantity 96 tests
Datasheet Datasheet

Recommended BMI1 Polycomb Ring Finger Oncogene Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122007
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122006
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346741
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our BMI1 Polycomb Ring Finger Oncogene products

Mansur, Brietzke, McIntyre, Cao, Lee, Japiassú, Chen, Lu, Lu, Li, Xu, Lin: "BDNF and BMI effects on brain structures of bipolar offspring: results from the global mood and brain science initiative." in: Acta psychiatrica Scandinavica, Vol. 136, Issue 6, pp. 607-614, (2018) (PubMed).

Zhou, Dai, Wu, Ji, Karaplis, Goltzman, Yang, Miao: "Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment." in: Scientific reports, Vol. 6, pp. 29171, (2018) (PubMed).

León-González, Jara-Palacios, Abbas, Heredia, Schini-Kerth: "Role of epigenetic regulation on the induction of apoptosis in Jurkat leukemia cells by white grape pomace rich in phenolic compounds." in: Food & function, Vol. 8, Issue 11, pp. 4062-4069, (2018) (PubMed).

Dauleh, Santeramo, Fielding, Ward, Herrmann, Murray, Wilm: "Characterisation of Cultured Mesothelial Cells Derived from the Murine Adult Omentum." in: PLoS ONE, Vol. 11, Issue 7, pp. e0158997, (2017) (PubMed).

Chen, Wang, Lee, Lee, Li, Hong, Hung, Chien, Chang, Hsu, Chang: "Hinokitiol up-regulates miR-494-3p to suppress BMI1 expression and inhibits self-renewal of breast cancer stem/progenitor cells." in: Oncotarget, Vol. 8, Issue 44, pp. 76057-76068, (2017) (PubMed).

Becker, Potapenko, Niklaus, Bieback, Ho, Müller: "Polycomb Protein BMI1 Regulates Osteogenic Differentiation of Human Adipose Tissue-Derived Mesenchymal Stem Cells Downstream of GSK3." in: Stem cells and development, Vol. 25, Issue 12, pp. 922-33, (2016) (PubMed).

Lin, Ouyang, Zhu, Huang, Liu, Chen, Cao, Li, Signer, Xu, Chung, Zhang, Lin, Patel, Wu, Cai, Hou, Wen, Jafari, Liu, Luo, Zhu, Qiu, Hou, Chen, Chen, Granet, Heichel, Shang, Li, Krawczyk et al.: "Lens regeneration using endogenous stem cells with gain of visual function. ..." in: Nature, Vol. 531, Issue 7594, pp. 323-8, (2016) (PubMed).

Zhou, Zhang, Pan, Wang, Yan, Fang, Munnee, Tang: "Bmi1 essentially mediates podocalyxin-enhanced Cisplatin chemoresistance in oral tongue squamous cell carcinoma." in: PLoS ONE, Vol. 10, Issue 4, pp. e0123208, (2015) (PubMed).

Jin, Lee, Heo, Lim, Kim, Kim, Nam, Hong, Cho, Choi, Kim, Shin, Kim: "Senescence associated MCP-1 secretion is dependent on a decline in BMI1 in human mesenchymal stromal cells." in: Antioxidants & redox signaling, (2015) (PubMed).

Shen, Chen, Ding, Qi, Cen, Wang, Yao, Chen: "BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression." in: Journal of cellular and molecular medicine, Vol. 18, Issue 6, pp. 1004-17, (2014) (PubMed).

Synonyms and alternative names related to BMI1 Polycomb Ring Finger Oncogene

BMI1 proto-oncogene, polycomb ring finger (BMI1), BMI1 polycomb ring finger oncogene (LOC100230513), Bmi1 polycomb ring finger oncogene (Bmi1), BMI1 proto-oncogene, polycomb ring finger (Bmi1), bmi1 polycomb ring finger oncogene 1a (bmi1a), bmi1 polycomb ring finger oncogene 1b (bmi1b), BMI1 proto-oncogene, polycomb ring finger L homeolog (bmi1.L), AW546694, Bmi-1, BMI-1, bmi-1, bmi1, bmi1-a, bmi1-b, bmi1b, FLVI2/BMI1, PCGF4, Pcgf4, pcgf4, pcgf4b, psc1, RNF51, rnf51, wu:fb17g03, wu:fd18f06, xbmi-1

Protein level used designations for BMI1 Polycomb Ring Finger Oncogene

  • B lymphoma Mo-MLV insertion region 1 homolog
  • flvi-2/bmi-1
  • murine leukemia viral (bmi-1) oncogene homolog
  • polycomb complex protein BMI-1
  • polycomb group RING finger protein 4
  • polycomb group protein Bmi1
  • ring finger protein 51
  • BMI1 polycomb ring finger oncogene
  • B lymphoma Mo-MLV insertion region 1
  • polycomb group ring finger 4
  • polycomb complex protein BMI-1-A
  • polycomb group RING finger protein 4-A
  • B lymphoma Mo-MLV insertion region
  • B lymphoma Mo-MLV insertion region 1b
  • Polycomb group RING finger protein 4-B
  • polycomb complex protein BMI-1-B
  • polycomb group RING finger protein 4-B
  • polycomb group ring finger 4 B
  • oncoprotein BMI-1
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