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BMF Products

(Bcl2 Modifying Factor (BMF))
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Featured BMF Categories

BMF Antibodies

High quality antibodies with extensive validation data.

BMF ELISA Kits

Reliable ELISA kits for a wide range of species.

BMF Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended BMF Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7442702
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IHC, ELISA, IP, ICC, FACS
Validations
  • (3)
Cat. No. ABIN2745519
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN388102
Quantity 400 μL
Datasheet Datasheet

Recommended BMF ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965128
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN512422
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative
Validations
Cat. No. ABIN778246
Quantity 96 tests
Datasheet Datasheet

Recommended BMF Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346739
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN666770
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415293
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our BMF products

Sul, Rajasekaran, Park, Suh, Choi: "MicroRNA-29b Enhances Osteoclast Survival by Targeting BCL-2-Modifying Factor after Lipopolysaccharide Stimulation." in: Oxidative medicine and cellular longevity, Vol. 2019, pp. 6018180, (2019) (PubMed).

Ten Hacken, Valentin, Regis, Sun, Yin, Werner, Deng, Gruber, Wong, Zheng, Gill, Seiler, Smith, Thomas, Buonamici, Ghia, Kim, Rassenti, Burger, Kipps, Meyerson, Bachireddy, Wang, Reed, Neuberg et al.: "Splicing modulation sensitizes chronic lymphocytic leukemia cells to venetoclax by remodeling mitochondrial apoptotic dependencies. ..." in: JCI insight, Vol. 3, Issue 19, (2018) (PubMed).

Chen, Felix, Wang: "Immune regulation through mitochondrion-dependent dendritic cell death induced by T regulatory cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 5684-92, (2011) (PubMed).

Gramantieri, Fornari, Ferracin, Veronese, Sabbioni, Calin, Grazi, Croce, Bolondi, Negrini: "MicroRNA-221 targets Bmf in hepatocellular carcinoma and correlates with tumor multifocality." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 16, pp. 5073-81, (2009) (PubMed).

Chen, Huang, Wang: "Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity." in: Blood, Vol. 109, Issue 10, pp. 4360-7, (2007) (PubMed).

Funke, Dakoji, Bredt: "Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions." in: Annual review of biochemistry, Vol. 74, pp. 219-45, (2005) (PubMed).

Heiser, Labi, Erlacher, Villunger: "The Bcl-2 protein family and its role in the development of neoplastic disease." in: Experimental gerontology, Vol. 39, Issue 8, pp. 1125-35, (2004) (PubMed).

Legouis, Jaulin-Bastard, Schott, Navarro, Borg, Labouesse: "Basolateral targeting by leucine-rich repeat domains in epithelial cells." in: EMBO reports, Vol. 4, Issue 11, pp. 1096-102, (2003) (PubMed).

Cory, Huang, Adams: "The Bcl-2 family: roles in cell survival and oncogenesis." in: Oncogene, Vol. 22, Issue 53, pp. 8590-607, (2003) (PubMed).

Saito, Santoni, Arsanto, Jaulin-Bastard, Le Bivic, Marchetto, Audebert, Isnardon, Adélaïde, Birnbaum, Borg: "Lano, a novel LAP protein directly connected to MAGUK proteins in epithelial cells." in: The Journal of biological chemistry, Vol. 276, Issue 34, pp. 32051-5, (2001) (PubMed).

Synonyms and alternative names related to BMF

Bcl2 modifying factor (BMF), Bcl2 modifying factor L homeolog (bmf.L), BCL2 modifying factor (Bmf), Bcl2 modifying factor (Bmf), AW260063, AW411872, BMF

Protein level used designations for BMF

  • Bcl2 modifying factor
  • bcl-2-modifying factor
  • Bcl-2 modifying factor
  • Bcl-2-modifying factor
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