BLM Products
(Bloom Syndrome RecQ Like Helicase (BLM))
Categories
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq, Jul 2008].
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Featured BLM Categories
BLM Antibodies
High quality antibodies with extensive validation data.
BLM ELISA Kits
Reliable ELISA kits for a wide range of species.
BLM Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BLM Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IHC (p), ICC
Validations
- (4)
Cat. No.
ABIN2855003
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7138888
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (2)
Cat. No.
ABIN651053
Quantity
400 μL
Datasheet
Datasheet
Recommended BLM ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1123945
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1123947
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Chicken
Analytical Method
Validations
Cat. No.
ABIN1123946
Quantity
96 tests
Datasheet
Datasheet
Recommended BLM Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346713
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3089946
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3132191
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our BLM products
: "Increased error-free DNA repair gene expression through reprogramming in human iPS cells." in: Regenerative therapy, Vol. 11, pp. 101-105, (2019) (PubMed).: "Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA." in: Molecular cell, Vol. 69, Issue 1, pp. 9-23.e6, (2018) (PubMed).
: "Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer." in: Molecular cancer therapeutics, Vol. 14, Issue 4, pp. 1057-65, (2015) (PubMed).
: "Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion." in: The EMBO journal, Vol. 34, Issue 10, pp. 1371-84, (2015) (PubMed).
: "The WRN and MUS81 proteins limit cell death and genome instability following oncogene activation." in: Oncogene, Vol. 32, Issue 5, pp. 610-20, (2013) (PubMed).
: "Altered RECQ Helicase Expression in Sporadic Primary Colorectal Cancers." in: Translational oncology, Vol. 6, Issue 4, pp. 458-69, (2013) (PubMed).
: "BLM helicase stimulates the ATPase and chromatin-remodeling activities of RAD54." in: Journal of cell science, Vol. 122, Issue Pt 17, pp. 3093-103, (2009) (PubMed).
: "HYD1-induced increase in reactive oxygen species leads to autophagy and necrotic cell death in multiple myeloma cells." in: Molecular cancer therapeutics, Vol. 8, Issue 8, pp. 2441-51, (2009) (PubMed).
: "Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress." in: Journal of molecular biology, Vol. 375, Issue 4, pp. 1152-64, (2008) (PubMed).
: "BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination." in: The Journal of cell biology, Vol. 178, Issue 1, pp. 9-14, (2007) (PubMed).
Synonyms and alternative names related to BLM
Bloom syndrome RecQ like helicase (BLM), Bloom syndrome RecQ like helicase S homeolog (blm.S), Bloom syndrome RecQ like helicase (Blm), Bloom syndrome, RecQ like helicase (Blm), blm-A, BS, ORF1, RECQ2, RECQL2, RECQL3, xBLMProtein level used designations for BLM
- Bloom syndrome protein
- DNA helicase, RecQ-like type 2
- recQ protein-like 3
- Bloom syndrome, RecQ helicase-like
- Bloom syndrome protein homolog
- recQ helicase homolog
- BLM helicase
- Gd BLM
- Bloom syndrome homolog
- mBLM
- Bloom syndrome protein-like
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