BLK Products
(B Lymphoid Tyrosine Kinase (BLK))
Categories
This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010].
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Featured BLK Categories
BLK Antibodies
High quality antibodies with extensive validation data.
BLK ELISA Kits
Reliable ELISA kits for a wide range of species.
BLK Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BLK Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro), ICC
Validations
- (6)
Cat. No.
ABIN7441157
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (5)
Cat. No.
ABIN560064
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN392087
Quantity
400 μL
Datasheet
Datasheet
Recommended BLK ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954026
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4885999
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951074
Quantity
96 tests
Datasheet
Datasheet
Recommended BLK Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346711
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346709
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121957
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our BLK products
: "BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling." in: PLoS ONE, Vol. 8, Issue 3, pp. e59842, (2013) (PubMed).: "Immune regulation through mitochondrion-dependent dendritic cell death induced by T regulatory cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 5684-92, (2011) (PubMed).
: "Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK. ..." in: Annals of the rheumatic diseases, Vol. 71, Issue 1, pp. 136-42, (2011) (PubMed).
: "Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese." in: Genes and immunity, Vol. 10, Issue 3, pp. 219-26, (2009) (PubMed).
: "Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 34, pp. 14460-5, (2009) (PubMed).
: "Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. ..." in: The New England journal of medicine, Vol. 358, Issue 9, pp. 900-9, (2008) (PubMed).
: "Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity." in: Blood, Vol. 109, Issue 10, pp. 4360-7, (2007) (PubMed).
: "Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." in: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).
Synonyms and alternative names related to BLK
BLK proto-oncogene, Src family tyrosine kinase (blk), BLK proto-oncogene, Src family tyrosine kinase (BLK), B lymphoid kinase (Blk), BLK proto-oncogene, Src family tyrosine kinase (Blk), bltk, MODY11, si:dkey-33i22.2, zgc:136231Protein level used designations for BLK
- B lymphoid kinase
- tyrosine-protein kinase Blk
- B lymphoid tyrosine kinase
- tyrosine-protein kinase Blk-like
- b lymphocyte kinase
- p55-Blk
- BLK nonreceptor tyrosine kinase
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