BIRC3 Products
(Baculoviral IAP Repeat Containing 3 (BIRC3))
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This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011].
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Featured BIRC3 Categories
BIRC3 Antibodies
High quality antibodies with extensive validation data.
BIRC3 ELISA Kits
Reliable ELISA kits for a wide range of species.
BIRC3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BIRC3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
WB, IHC, IF
Validations
- (8)
Cat. No.
ABIN7073179
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (4)
Cat. No.
ABIN657941
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN1678920
Quantity
100 μg
Datasheet
Datasheet
Recommended BIRC3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6975606
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN625459
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4885857
Quantity
96 tests
Datasheet
Datasheet
Recommended BIRC3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346688
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3090140
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3131334
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our BIRC3 products
: "Prolonged lipopolysaccharide exposure induces transient immunosuppression in BV2 microglia." in: Journal of cellular physiology, Vol. 234, Issue 2, pp. 1889-1903, (2019) (PubMed).: "Cellular inhibitor of apoptosis protein 2 promotes the epithelial-mesenchymal transition in triple-negative breast cancer cells through activation of the AKT signaling pathway." in: Oncotarget, Vol. 8, Issue 45, pp. 78781-78795, (2018) (PubMed).
: "Perfluorodecanoic acid stimulates NLRP3 inflammasome assembly in gastric cells." in: Scientific reports, Vol. 7, pp. 45468, (2018) (PubMed).
: "Genome-wide gene expression array identifies novel genes related to disease severity and excessive daytime sleepiness in patients with obstructive sleep apnea." in: PLoS ONE, Vol. 12, Issue 5, pp. e0176575, (2017) (PubMed).
: "Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation." in: Scientific reports, Vol. 5, pp. 8293, (2015) (PubMed).
: "Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer." in: Journal of bioenergetics and biomembranes, (2015) (PubMed).
: "Cellular inhibitor of apoptosis protein 2 controls human colonic epithelial restitution, migration, and Rac1 activation." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 308, Issue 2, pp. G92-9, (2015) (PubMed).
: "NPD1-mediated stereoselective regulation of BIRC3 expression through cREL is decisive for neural cell survival." in: Cell death and differentiation, Vol. 22, Issue 8, pp. 1363-77, (2015) (PubMed).
: "Antibody validation by combining immunohistochemistry and protein extraction from formalin-fixed paraffin-embedded tissues." in: Histopathology, Vol. 60, Issue 6B, pp. E37-50, (2012) (PubMed).
: "Phase I trial of induction histone deacetylase and proteasome inhibition followed by surgery in non-small-cell lung cancer." in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 7, Issue 11, pp. 1683-90, (2012) (PubMed).
Synonyms and alternative names related to BIRC3
baculoviral IAP repeat containing 3 (BIRC3), baculoviral IAP repeat-containing 3 (Birc3), baculoviral IAP repeat-containing protein 3 (LOC100399118), inhibitor of apoptosis protein-2 (OpmnVgp074), AIP1, Api1, API2, Api2, AW107670, Birc2, BIRC2, c-IAP2, cIAP-1, cIAP-2, cIAP1, CIAP2, cIAP2, HAIP1, HIAP1, HIAP2, IAP1, IAP2, MALT2, MIAP1, MIAP2, MIHB, MIHC, RNF49Protein level used designations for BIRC3
- IAP homolog C
- IAP-1
- RING finger protein 49
- TNFR2-TRAF signaling complex protein
- TNFR2-TRAF-signaling complex protein 1
- apoptosis inhibitor 2
- baculoviral IAP repeat-containing 3
- baculoviral IAP repeat-containing protein 3
- inhibitor of apoptosis protein 1
- mammalian IAP homolog C
- apoptosis inhibitor 1
- baculoviral IAP repeat-containing 2
- mIAP-1
- baculoviral IAP repeat-containing protein 3-like
- inhibitor of apoptosis protein-2
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