BIRC2 Products
(Baculoviral IAP Repeat Containing 2 (BIRC2))
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The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
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Featured BIRC2 Categories
BIRC2 Antibodies
High quality antibodies with extensive validation data.
BIRC2 ELISA Kits
Reliable ELISA kits for a wide range of species.
BIRC2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BIRC2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7145198
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6260268
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, PLA
Validations
- (2)
Cat. No.
ABIN513396
Quantity
100 μg
Datasheet
Datasheet
Recommended BIRC2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965114
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6974985
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4882354
Quantity
96 tests
Datasheet
Datasheet
Recommended BIRC2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346686
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7414822
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7401638
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our BIRC2 products
: "Prolonged lipopolysaccharide exposure induces transient immunosuppression in BV2 microglia." in: Journal of cellular physiology, Vol. 234, Issue 2, pp. 1889-1903, (2019) (PubMed).: "IAPs cause resistance to TRAIL-dependent apoptosis in follicular thyroid cancer." in: Endocrine-related cancer, Vol. 25, Issue 3, pp. 295-308, (2019) (PubMed).
: "Cellular inhibitor of apoptosis protein 1 (cIAP1) stability contributes to YM155 resistance in human gastric cancer cells." in: The Journal of biological chemistry, Vol. 290, Issue 16, pp. 9974-85, (2015) (PubMed).
: "Anti-apoptotic protein BRE/BRCC45 attenuates apoptosis through maintaining the expression of caspase inhibitor XIAP in mouse Lewis lung carcinoma D122 cells." in: Apoptosis : an international journal on programmed cell death, Vol. 19, Issue 5, pp. 829-40, (2014) (PubMed).
: "Ischemic preconditioning reduces neurovascular damage after hypoxia-ischemia via the cellular inhibitor of apoptosis 1 in neonatal brain." in: Stroke; a journal of cerebral circulation, Vol. 44, Issue 1, pp. 162-9, (2012) (PubMed).
: "cIAP1 cooperatively inhibits procaspase-3 activation by the caspase-9 apoptosome." in: The Journal of biological chemistry, Vol. 285, Issue 39, pp. 30061-8, (2010) (PubMed).
: "Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function." in: The Journal of clinical investigation, Vol. 115, Issue 10, pp. 2673-8, (2005) (PubMed).
: "Expression and localization of inhibitor of apoptosis proteins in normal human tissues." in: Human pathology, Vol. 37, Issue 1, pp. 78-86, (2005) (PubMed).
: "Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 29, pp. 10774-9, (2004) (PubMed).
: "The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys." in: Nature, Vol. 427, Issue 6977, pp. 848-53, (2004) (PubMed).
Synonyms and alternative names related to BIRC2
baculoviral IAP repeat containing 2 (BIRC2), baculoviral IAP repeat-containing 2 (Birc2), baculoviral IAP repeat containing 2 (birc2), baculoviral IAP repeat containing 2 L homeolog (birc2.L), API1, Api1, api1, Api2, AW146227, birc2, Birc3, birc3, c-IAP1, c-iap1, ciap-1, cIAP1, ciap1, cIAP2, Hiap-2, hiap-2, HIAP1, HIAP2, hiap2, IAP1, IAP2, ITA, mcIAP1, MIAP1, MIAP2, MIHB, mihb, MIHC, rIAP1, RNF48, rnf48Protein level used designations for BIRC2
- IAP homolog B
- IAP-2
- NFR2-TRAF signalling complex protein
- RING finger protein 48
- TNFR2-TRAF-signaling complex protein 2
- apoptosis inhibitor 1
- baculoviral IAP repeat-containing 2
- baculoviral IAP repeat-containing protein 2
- inhibitor of apoptosis protein 2
- apoptosis inhibitor 2
- inhibitor of apoptosis protein
- IAP homolog
- inhibitor of T-cell apoptosis protein
- inhibitor of apoptosis 1
- baculoviral IAP repeat-containing 3
- mIAP-2
- inhibitor of apoptosis protein-1
- inhibitor of apoptosis protein 1
- bZ1P14.6.2 (baculoviral IAP repeat-containing 3 )
- baculoviral IAP repeat containing 2 L homeolog
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