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BICD2 Products

(Bicaudal D Homolog 2 (BICD2))

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This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described. [provided by RefSeq, Jul 2008].

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Featured BICD2 Categories

BICD2 Antibodies

High quality antibodies with extensive validation data.

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Latest Publications for our BICD2 products

Lee, Jung, Oh, Choi, Chae, Kim, Lim, Kim, Lee, Seong, Han: "BICD1 mediates HIF1α nuclear translocation in mesenchymal stem cells during hypoxia adaptation." in: Cell death and differentiation, (2018) (PubMed).

Terenzio, Golding, Russell, Wicher, Rosewell, Spencer-Dene, Ish-Horowicz, Schiavo: "Bicaudal-D1 regulates the intracellular sorting and signalling of neurotrophin receptors." in: The EMBO journal, Vol. 33, Issue 14, pp. 1582-98, (2014) (PubMed).

Teuling, van Dis, Wulf, Haasdijk, Akhmanova, Hoogenraad, Jaarsma: "A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice." in: Human molecular genetics, Vol. 17, Issue 18, pp. 2849-62, (2008) (PubMed).

Holland, Milne, Garka, Johnson, Willis, Sims, Rauch, Bird, Virca: "Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2." in: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 16229-40, (2002) (PubMed).

Hoogenraad, Akhmanova, Howell, Dortland, De Zeeuw, Willemsen, Visser, Grosveld, Galjart: "Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes." in: The EMBO journal, Vol. 20, Issue 15, pp. 4041-54, (2001) (PubMed).

Synonyms and alternative names related to BICD2

BICD cargo adaptor 2 (BICD2), bicaudal D homolog 2 (Drosophila) (Bicd2), BICD cargo adaptor 2 (Bicd2), BICD cargo adaptor 2 L homeolog (bicd2.L), BICD cargo adaptor 2 (bicd2), zgc:171572 (zgc:171572), 0610027D24Rik, 1110005D12Rik, AA408834, bA526D8.1, BICD2, bicd2, MGC84972, mKIAA0699, SMALED2

Protein level used designations for BICD2

  • bic-D 2
  • coiled-coil protein BICD2
  • cytoskeleton-like bicaudal D protein homolog 2
  • homolog of Drosophila bicaudal D
  • protein bicaudal D homolog 2
  • bicaudal D homolog 2
  • bicaudal D protein
  • bicaudal D homolog 2 (Drosophila)
  • protein bicaudal D homolog 2-like
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