BCLAF1 Products
(BCL2-Associated Transcription Factor 1 (BCLAF1))
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This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured BCLAF1 Categories
BCLAF1 Antibodies
High quality antibodies with extensive validation data.
Recommended BCLAF1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
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Cat. No.
ABIN654941
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
Cat. No.
ABIN7145288
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
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Cat. No.
ABIN6257960
Quantity
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Datasheet
Datasheet
Latest Publications for our BCLAF1 products
: "BclAF1 restriction factor is neutralized by proteasomal degradation and microRNA repression during human cytomegalovirus infection." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 24, pp. 9575-80, (2012) (PubMed).: "BCLAF1 is a radiation-induced H2AX-interacting partner involved in γH2AX-mediated regulation of apoptosis and DNA repair." in: Cell death & disease, Vol. 3, pp. e359, (2012) (PubMed).
: "Tandem array-based expression screens identify host mRNA targets of virus-encoded microRNAs." in: Nature genetics, Vol. 41, Issue 1, pp. 130-4, (2008) (PubMed).
: "Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage." in: Molecular and cellular biology, Vol. 27, Issue 24, pp. 8480-91, (2007) (PubMed).
: "Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins." in: Molecular and cellular biology, Vol. 19, Issue 6, pp. 4390-404, (1999) (PubMed).
Synonyms and alternative names related to BCLAF1
BCL2-associated transcription factor 1 (Bclaf1), BCL2 associated transcription factor 1 (BCLAF1), BCL2 associated transcription factor 1 (bclaf1), mitochondrial fission regulator 2 (MTFR2), BCL2 associated transcription factor 1 (Bclaf1), 2610102K23Rik, 2700025J07Rik, 2810454G14Rik, 5730534O06Rik, Aa2-041, AI450190, AW556225, BCLAF1, bk211l9.1, bK211L9.1, Btf, btf, BTF, DKFZp468F0113, Fam54a, mKIAA0164, Mtfr2Protein level used designations for BCLAF1
- bcl-2-associated transcription factor 1
- mitochondrial fission regulator 2
- protein FAM54A
- BCL2-associated transcription factor 1
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