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BCL3 Products

(B-Cell CLL/lymphoma 3 (BCL3))

Categories

This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008].

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Featured BCL3 Categories

BCL3 Antibodies

High quality antibodies with extensive validation data.

BCL3 ELISA Kits

Reliable ELISA kits for a wide range of species.

BCL3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended BCL3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN6137509
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7145162
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IF, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN653286
Quantity 400 μL
Datasheet Datasheet

Recommended BCL3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965110
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5593494
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative
Validations
Cat. No. ABIN778229
Quantity 96 tests
Datasheet Datasheet

Recommended BCL3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121961
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346574
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413781
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our BCL3 products

Gehrke, Wörns, Huber, Hess, Straub, Hövelmeyer, Waisman, Kim, Schuppan, Galle, Schattenberg: "Hepatic B cell leukemia-3 promotes hepatic steatosis and inflammation through insulin-sensitive metabolic transcription factors." in: Journal of hepatology, Vol. 65, Issue 6, pp. 1188-1197, (2018) (PubMed).

Wang, Xiong, Hu, Sun, Ma: "MicroRNA-19b inhibits proliferation of gastric cancer cells by targeting B-cell CLL/lymphoma 3." in: Oncology reports, Vol. 36, Issue 4, pp. 2079-86, (2016) (PubMed).

Gringhuis, Kaptein, Wevers, Mesman, Geijtenbeek: "Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKK?- and CYLD-dependent Bcl3 activation." in: Nature communications, Vol. 5, pp. 3898, (2014) (PubMed).

Khan, Coaquette, Davrinche, Herbein: "Bcl-3-regulated transcription from major immediate-early promoter of human cytomegalovirus in monocyte-derived macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 12, pp. 7784-94, (2009) (PubMed).

Mitchell, Thompson, Trent, Casella: "A short domain within Bcl-3 is responsible for its lymphocyte survival activity." in: Annals of the New York Academy of Sciences, Vol. 975, pp. 132-47, (2003) (PubMed).

Elliott, Coon, Hays, Stadheim, Vincenti: "Bcl-3 is an interleukin-1-responsive gene in chondrocytes and synovial fibroblasts that activates transcription of the matrix metalloproteinase 1 gene." in: Arthritis and rheumatism, Vol. 46, Issue 12, pp. 3230-9, (2002) (PubMed).

Mitchell, Hildeman, Kedl, Teague, Schaefer, White, Zhu, Kappler, Marrack: "Immunological adjuvants promote activated T cell survival via induction of Bcl-3." in: Nature immunology, Vol. 2, Issue 5, pp. 397-402, (2001) (PubMed).

Synonyms and alternative names related to BCL3

B-cell CLL/lymphoma 3 (BCL3), B cell leukemia/lymphoma 3 (Bcl3), B-cell CLL/lymphoma 3 (Bcl3), AI528691, Bcl-3, BCL3, BCL4, D19S37

Protein level used designations for BCL3

  • B-cell CLL/lymphoma 3
  • B-cell leukemia/lymphoma 3
  • B-cell lymphoma 3 protein homolog
  • B-cell lymphoma 3 protein
  • B-cell lymphoma 3-encoded protein
  • BCL-3
  • chronic lymphatic leukemia protein
  • proto-oncogene BCL3
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