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BCL2L10 Products

(BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

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The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq, Jul 2008].

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Featured BCL2L10 Categories

BCL2L10 Antibodies

High quality antibodies with extensive validation data.

BCL2L10 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended BCL2L10 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (7)
Cat. No. ABIN5611302
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS, Neut
Validations
  • (4)
Cat. No. ABIN5611303
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS
Validations
  • (3)
Cat. No. ABIN6243511
Quantity 200 μL
Datasheet Datasheet

Recommended BCL2L10 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6226676
Quantity 96 tests
Datasheet Datasheet

Recommended BCL2L10 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN1098488
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346554
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346556
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our BCL2L10 products

Guérin, Cornut-Thibaut, Giscard-Destaing, Pouvreau, Guillemin, Aouacheria: "Subcellular dynamics of the maternal cell death regulator BCL2L10 in human preimplantation embryos." in: Human reproduction (Oxford, England), Vol. 28, Issue 3, pp. 729-39, (2013) (PubMed).

Guillemin, Lalle, Gillet, Guerin, Hamamah, Aouacheria: "Oocytes and early embryos selectively express the survival factor BCL2L10." in: Journal of molecular medicine (Berlin, Germany), Vol. 87, Issue 9, pp. 923-40, (2009) (PubMed).

Heiser, Labi, Erlacher, Villunger: "The Bcl-2 protein family and its role in the development of neoplastic disease." in: Experimental gerontology, Vol. 39, Issue 8, pp. 1125-35, (2004) (PubMed).

Cory, Huang, Adams: "The Bcl-2 family: roles in cell survival and oncogenesis." in: Oncogene, Vol. 22, Issue 53, pp. 8590-607, (2003) (PubMed).

Ke, Godzik, Reed: "Bcl-B, a novel Bcl-2 family member that differentially binds and regulates Bax and Bak." in: The Journal of biological chemistry, Vol. 276, Issue 16, pp. 12481-4, (2001) (PubMed).

Synonyms and alternative names related to BCL2L10

BCL2 like 10 (BCL2L10), Bcl2-like 10 (Bcl2l10), BCL2 like 10 (Bcl2l10), BCL2-like 10 (apoptosis facilitator) (bcl2l10), AA420380, AU023065, BCL-B, Boo, C85687, Diva, mcl1l, NR-13, nr13, sb:cb78

Protein level used designations for BCL2L10

  • anti-apoptotic protein NrH
  • apoptosis regulator Bcl-B
  • bcl-2-like protein 10
  • bcl2-L-10
  • anti-apoptotic protein Boo
  • bcl-2 homolog Diva
  • Boo/DIVA
  • nrz
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