BCL2L1 Products
(BCL2-Like 1 (BCL2L1))
Categories
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008].
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Featured BCL2L1 Categories
BCL2L1 Antibodies
High quality antibodies with extensive validation data.
BCL2L1 ELISA Kits
Reliable ELISA kits for a wide range of species.
BCL2L1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BCL2L1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, PLA
Validations
- (1)
- (6)
Cat. No.
ABIN560043
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP, IHC (p), ICC
Validations
- (1)
- (7)
Cat. No.
ABIN2856151
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (1)
- (6)
Cat. No.
ABIN1512625
Quantity
100 μg
Datasheet
Datasheet
Recommended BCL2L1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6954062
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965126
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962054
Quantity
96 tests
Datasheet
Datasheet
Recommended BCL2L1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7092729
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121986
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121985
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our BCL2L1 products
: "O‑GlcNAc modification influences endometrial receptivity by promoting endometrial cell proliferation, migration and invasion." in: Oncology reports, Vol. 42, Issue 5, pp. 2065-2074, (2020) (PubMed).: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).
: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).
: "Active targeting co-delivery system based on hollow mesoporous silica nanoparticles for antitumor therapy in ovarian cancer stem-like cells." in: Oncology reports, Vol. 38, Issue 3, pp. 1442-1450, (2018) (PubMed).
: "Emodin alleviates severe acute pancreatitis-associated acute lung injury by decreasing pre-B-cell colony-enhancing factor expression and promoting polymorphonuclear neutrophil apoptosis." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 5121-5128, (2018) (PubMed).
: "Grape Seed Proanthocyanidin Extract Prevents Ovarian Aging by Inhibiting Oxidative Stress in the Hens." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 9390810, (2018) (PubMed).
: "Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 390, Issue 4, pp. 379-395, (2017) (PubMed).
: "Photodynamic Therapy Using Indolines-Fused-Triazoles Induces Mitochondrial Apoptosis in Human Non-Melanoma BCC Cells." in: Anticancer research, Vol. 37, Issue 10, pp. 5499-5505, (2017) (PubMed).
: "Growth of tyrosine kinase inhibitor-resistant Philadelphia-positive acute lymphoblastic leukemia: Role of bone marrow stromal cells." in: Oncology letters, Vol. 13, Issue 4, pp. 2059-2070, (2017) (PubMed).
: "Expression Profile of BCL-2, BCL-XL, and MCL-1 Predicts Pharmacological Response to the BCL-2 Selective Antagonist Venetoclax in Multiple Myeloma Models." in: Molecular cancer therapeutics, Vol. 15, Issue 5, pp. 1132-44, (2016) (PubMed).
Synonyms and alternative names related to BCL2L1
BCL2 like 1 (BCL2L1), BCL2-like 1 (Bcl2l1), Bcl2-like 1 (Bcl2l1), BCL2 like 1 (bcl2l1), BCL2-like 1 L homeolog (bcl2l1.L), BCL2 like 1 (Bcl2l1), bcl2-like 1 (bcl2l1), Bcl(X)L, Bcl-X, bcl-x, bcl-X, bcl-x(l), bcl-xL, Bcl-XL, Bcl-xl, Bcl-xL, BCL-XL, bcl-XL, bcl-xl, BCL-XL/S, bcl-xl/s, bcl-xS, Bcl-Xs, bcl-xs, BCL2L, Bcl2l, bcl2l, BCL2L1, BCLX, BclX, Bclx, bclx, BCLXL, bclxl, BCLXS, blp1, cb1021, PPP1R52, xR11, zfBLP1Protein level used designations for BCL2L1
- apoptosis regulator Bcl-X
- bcl-2-like protein 1
- protein phosphatase 1, regulatory subunit 52
- B-cell leukemia/lymphoma x
- anti-apoptosis regulatory protein
- bcl2-L-1
- B cell lymphoma 2 like
- B cell lymphoma like X
- BCL2-like protein 1
- anti-apoptotic Bcl-xL
- BCLX protein
- BCL2-like 1
- Bcl-X
- apoptosis regulator R11
- Bcl-xL-like protein 1
- bcl-XL
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