BCL2A1 Products
(BCL2-Related Protein A1 (BCL2A1))
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This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured BCL2A1 Categories
BCL2A1 Antibodies
High quality antibodies with extensive validation data.
BCL2A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
BCL2A1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BCL2A1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN388092
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
Cat. No.
ABIN650621
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7145318
Quantity
100 μg
Datasheet
Datasheet
Recommended BCL2A1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954065
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975492
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1123380
Quantity
96 tests
Datasheet
Datasheet
Recommended BCL2A1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121988
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346548
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346550
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our BCL2A1 products
: "Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways." in: Oncotarget, Vol. 7, Issue 45, pp. 73080-73100, (2016) (PubMed).: "Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-kappaB-dependent pathways." in: Journal of hepatology, Vol. 51, Issue 1, pp. 139-48, (2009) (PubMed).
: "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity." in: Occupational and environmental medicine, Vol. 66, Issue 12, pp. 848-53, (2009) (PubMed).
: "Mitogen-activated protein kinase inhibition induces translocation of Bmf to promote apoptosis in melanoma." in: Cancer research, Vol. 69, Issue 5, pp. 1985-94, (2009) (PubMed).
: "Sirolimus-eluting versus bare-metal low-profile stent for renal artery treatment (GREAT Trial): angiographic follow-up after 6 months and clinical outcome up to 2 years." in: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, Vol. 14, Issue 4, pp. 460-8, (2007) (PubMed).
: "Weight loss reduces adipose tissue cathepsin S and its circulating levels in morbidly obese women." in: The Journal of clinical endocrinology and metabolism, Vol. 91, Issue 3, pp. 1042-7, (2006) (PubMed).
: "Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma." in: Cancer research, Vol. 65, Issue 19, pp. 8869-77, (2005) (PubMed).
: "Up-regulation of Bfl-1/A1 via NF-kappaB activation in cisplatin-resistant human bladder cancer cell line." in: Cancer letters, Vol. 212, Issue 1, pp. 61-70, (2004) (PubMed).
: "Cell death in the third millennium." in: Cell death and differentiation, Vol. 7, Issue 1, pp. 2-7, (2000) (PubMed).
: "Structural basis of BFL-1 for its interaction with BAX and its anti-apoptotic action in mammalian and yeast cells." in: The Journal of biological chemistry, Vol. 275, Issue 15, pp. 11092-9, (2000) (PubMed).
Synonyms and alternative names related to BCL2A1
BCL2 related protein A1 (BCL2A1), BCL2-related protein A1 (Bcl2a1), BCL2-related protein A1 (BCL2A1), ACC-1, ACC-2, BCL2A1, Bcl2a1d, BCL2L5, BFL1, GRS, HBPA1Protein level used designations for BCL2A1
- bcl-2-like protein 5
- bcl-2-related protein A1
- bcl2-L-5
- hematopoietic BCL2-related protein A1
- hemopoietic-specific early response protein
- protein BFL-1
- B-cell leukemia/lymphoma 2 related protein A1
- B-cell leukemia/lymphoma 2 related protein A1d
- BCL2-related protein A1d
- protein A1
- Bcl-2-like protein 5
- BCL2-related protein A1
- Bcl-2-related protein A1
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