BCL10 Products
(B-Cell CLL/lymphoma 10 (BCL10))
Categories
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq, Jul 2008].
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Featured BCL10 Categories
BCL10 Antibodies
High quality antibodies with extensive validation data.
BCL10 ELISA Kits
Reliable ELISA kits for a wide range of species.
BCL10 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BCL10 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (2)
- (4)
Cat. No.
ABIN1724629
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
- (4)
Cat. No.
ABIN1944800
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, FACS, IHC (p)
Validations
- (4)
Cat. No.
ABIN654655
Quantity
400 μL
Datasheet
Datasheet
Recommended BCL10 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965103
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962056
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4881949
Quantity
96 tests
Datasheet
Datasheet
Recommended BCL10 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346536
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2128105
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7417939
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our BCL10 products
: "Platelet-activating factor-induced NF-kappaB activation and IL-8 production in intestinal epithelial cells are Bcl10-dependent." in: Inflammatory bowel diseases, Vol. 16, Issue 4, pp. 593-603, (2010) (PubMed).: "Toll-like receptor 4 mediates induction of the Bcl10-NFkappaB-interleukin-8 inflammatory pathway by carrageenan in human intestinal epithelial cells." in: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10550-8, (2008) (PubMed).
: "Development, evaluation, and application of a highly sensitive microtiter plate ELISA for human Bcl10 protein." in: Journal of immunoassay & immunochemistry, Vol. 28, Issue 3, pp. 173-88, (2007) (PubMed).
: "A preferential role for STAT5, not constitutively active STAT3, in promoting survival of a human lymphoid tumor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 8, pp. 5032-40, (2006) (PubMed).
: "MALT lymphoma with t(14;18)(q32;q21)/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression." in: The Journal of pathology, Vol. 205, Issue 3, pp. 293-301, (2005) (PubMed).
: "Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells." in: Nature immunology, Vol. 4, Issue 9, pp. 857-65, (2003) (PubMed).
: "Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21405-9, (2001) (PubMed).
: "Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway." in: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19012-9, (2001) (PubMed).
: "BCL10 expression in normal and neoplastic lymphoid tissue. Nuclear localization in MALT lymphoma." in: The American journal of pathology, Vol. 157, Issue 4, pp. 1147-54, (2000) (PubMed).
: "BCL10 gene mutation in lymphoma." in: Blood, Vol. 95, Issue 12, pp. 3885-90, (2000) (PubMed).
Synonyms and alternative names related to BCL10
B-cell CLL/lymphoma 10 (BCL10), B-cell CLL/lymphoma 10 (Bcl10), B-cell CLL/lymphoma 10 (bcl10), B-cell lymphoma/leukemia 10-like (LOC100223183), B cell leukemia/lymphoma 10 (Bcl10), B-cell lymphoma/leukemia 10 (bcl10), AI132454, BCL-10, BCL10, bcl10, c-E10, C81403, CARMEN, cE10, CIPER, CLAP, mE10, ME10Protein level used designations for BCL10
- B-cell lymphoma/leukemia 10
- CARD containing molecule enhancing NF-kB
- CARD-containing apoptotic signaling protein
- CARD-containing molecule enhancing NF-kappa-B
- CARD-containing proapoptotic protein
- CED-3/ICH-1 prodomain homologous E10-like regulator
- cCARMEN
- caspase-recruiting domain-containing protein
- cellular homolog of vCARMEN
- cellular-E10
- hCLAP
- mammalian CARD-containing adapter molecule E10
- B-cell leukemia/lymphoma 10
- R-RCD1
- RCD
- bcl-10
- B-cell lymophoma 10 protein
- B-cell CLL/lymphoma 10
- B cell lymphoma/leukemia 10
- CARD-like apoptotic protein
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