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(Brevican (BCAN))
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This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011].
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BCAN Antibodies
High quality antibodies with extensive validation data.
BCAN ELISA Kits
Reliable ELISA kits for a wide range of species.
BCAN Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BCAN Antibodies
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Reactivity
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Mouse
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ABIN7443593
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Cat. No.
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Recommended BCAN ELISA Kits
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ABIN6965238
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Cat. No.
ABIN1346486
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Latest Publications for our BCAN products
: "Required growth facilitators propel axon regeneration across complete spinal cord injury." in: Nature, Vol. 561, Issue 7723, pp. 396-400, (2019) (PubMed).: "Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells." in: BMC cancer, Vol. 12, pp. 358, (2012) (PubMed).
: "The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 19, pp. 10116-21, (1997) (PubMed).
: "Brevican, a chondroitin sulfate proteoglycan of rat brain, occurs as secreted and cell surface glycosylphosphatidylinositol-anchored isoforms." in: The Journal of biological chemistry, Vol. 270, Issue 45, pp. 27206-12, (1995) (PubMed).
: "Molecular cloning of brevican, a novel brain proteoglycan of the aggrecan/versican family." in: The Journal of biological chemistry, Vol. 269, Issue 13, pp. 10119-26, (1994) (PubMed).
Synonyms and alternative names related to BCAN
brevican (bcan), brevican (BCAN), brevican L homeolog (bcan.L), brevican (Bcan), ALPBRE, BCAN, BEHAB, Cspg7, CSPG7, fi32a12, wu:fi32a12, XbcanProtein level used designations for BCAN
- brevican core protein
- brevican
- brevican core protein-like
- brevican soluble core protein
- Brevican core protein
- brain-enriched hyaluronan-binding protein
- BEHAB
- brevican (brain specific proteoglycan in the aggrecan family)
- chondroitin sulfate proteoglycan 7
- chondroitin sulfate proteoglycan BEHAB
- chondroitin sulfate proteoglycan BEHAB/brevican
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