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B4GALT6 Products

(UDP-Gal:betaGlcNAc beta 1,4-Galactosyltransferase, Polypeptide 6 (B4GALT6))
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose\; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis. [provided by RefSeq, Jul 2008].

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Featured B4GALT6 Categories

B4GALT6 Antibodies

High quality antibodies with extensive validation data.

B4GALT6 ELISA Kits

Reliable ELISA kits for a wide range of species.

B4GALT6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended B4GALT6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN654654
Quantity 400 μL
Datasheet Datasheet
Reactivity Bat, Chicken, Cow, Dog, Horse, Human, Monkey, Mouse, Rabbit, Xenopus laevis
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN6746271
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), EIA
Validations
  • (3)
Cat. No. ABIN950594
Quantity 0.4 mL
Datasheet Datasheet

Recommended B4GALT6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1123505
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1123504
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1123506
Quantity 96 tests
Datasheet Datasheet

Recommended B4GALT6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346328
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346327
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3107934
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our B4GALT6 products

Dzwonek, Preobrazhenska, Cazzola, Conidi, Schellens, van Dinther, Stubbs, Klippel, Huylebroeck, ten Dijke, Verschueren: "Smad3 is a key nonredundant mediator of transforming growth factor beta signaling in Nme mouse mammary epithelial cells." in: Molecular cancer research : MCR, Vol. 7, Issue 8, pp. 1342-53, (2009) (PubMed).

Hayes, Chawla, Corvera: "TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2." in: The Journal of cell biology, Vol. 158, Issue 7, pp. 1239-49, (2002) (PubMed).

Lehmann, Janda, Pierreux, Rytömaa, Schulze, McMahon, Hill, Beug, Downward: "Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells." in: Genes & development, Vol. 14, Issue 20, pp. 2610-22, (2000) (PubMed).

Synonyms and alternative names related to B4GALT6

beta-1,4-galactosyltransferase 6 (B4GALT6), UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 (B4galt6), beta-1,4-galactosyltransferase 6 (B4galt6), AA536803, AU022389, B4Gal-T6, beta4Gal-T6

Protein level used designations for B4GALT6

  • UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6
  • UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase
  • UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6
  • beta-1,4-GalTase 6
  • beta-1,4-galactosyltransferase 6
  • beta4GalT-VI
  • b4Gal-T6
  • beta-1, 4-galactosyltransferase VI
  • beta4Gal-T6
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