BAK1 Products
(BCL2-Antagonist/killer 1 (BAK1))
Categories
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008].
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Featured BAK1 Categories
BAK1 Antibodies
High quality antibodies with extensive validation data.
BAK1 ELISA Kits
Reliable ELISA kits for a wide range of species.
BAK1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BAK1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC, Neut
Validations
- (6)
Cat. No.
ABIN5611250
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP
Validations
- (8)
Cat. No.
ABIN3020677
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (2)
- (10)
Cat. No.
ABIN3042342
Quantity
100 μg
Datasheet
Datasheet
Recommended BAK1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965129
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965130
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954055
Quantity
96 tests
Datasheet
Datasheet
Recommended BAK1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1346390
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346392
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7396205
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our BAK1 products
: "YWHAZ amplification/overexpression defines aggressive bladder cancer and contributes to chemo-/radio-resistance by suppressing caspase-mediated apoptosis." in: The Journal of pathology, (2019) (PubMed).: "Copper induces oxidative stress and apoptosis through mitochondria-mediated pathway in chicken hepatocytes." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 54, pp. 310-316, (2019) (PubMed).
: "MicroRNA-29c Correlates with Neuroprotection Induced by FNS by Targeting Both Birc2 and Bak1 in Rat Brain after Stroke." in: CNS neuroscience & therapeutics, Vol. 21, Issue 6, pp. 496-503, (2016) (PubMed).
: "Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane Permeability." in: Molecular neurobiology, (2015) (PubMed).
: "Ovatodiolide sensitizes aggressive breast cancer cells to doxorubicin, eliminates their cancer stem cell-like phenotype, and reduces doxorubicin-associated toxicity." in: Cancer letters, Vol. 364, Issue 2, pp. 125-34, (2015) (PubMed).
: "Notch4 Signaling Confers Susceptibility to TRAIL-Induced Apoptosis in Breast Cancer Cells." in: Journal of cellular biochemistry, Vol. 116, Issue 7, pp. 1371-80, (2015) (PubMed).
: "Regulation of cell transformation by Rb-controlled redox homeostasis." in: PLoS ONE, Vol. 9, Issue 7, pp. e102582, (2014) (PubMed).
: "The C-terminal domain (CTD) in linker histones antagonizes anti-apoptotic proteins to modulate apoptotic outcomes at the mitochondrion." in: Cell death & disease, Vol. 5, pp. e1058, (2014) (PubMed).
: "Systems analysis of BCL2 protein family interactions establishes a model to predict responses to chemotherapy." in: Cancer research, Vol. 73, Issue 2, pp. 519-28, (2013) (PubMed).
: "Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells." in: Cell death and differentiation, Vol. 19, Issue 12, pp. 1928-38, (2012) (PubMed).
Synonyms and alternative names related to BAK1
BCL2 antagonist/killer 1 (BAK1), BCL2-antagonist/killer 1 (Bak1), BCL2 antagonist/killer 1 (Bak1), BCL2 antagonist/killer 1 L homeolog (bak1.L), BAK, Bak, bak, BAK-LIKE, Bak1, bak1, BCL2L7, CDN1, N-Bak, N-BAK1Protein level used designations for BAK1
- BCL2-like 7 protein
- apoptosis regulator BAK
- bcl-2 homologous antagonist/killer
- bcl-2-like protein 7
- bcl2-L-7
- pro-apoptotic protein BAK
- Bcl2 homologous antagonist/killer
- Bcl-2-like 7
- BCL2 antagonist/killer 1 L homeolog
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