BAG3 Products
(BCL2-Associated Athanogene 3 (BAG3))
Categories
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008].
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Featured BAG3 Categories
BAG3 Antibodies
High quality antibodies with extensive validation data.
BAG3 ELISA Kits
Reliable ELISA kits for a wide range of species.
BAG3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BAG3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (5)
Cat. No.
ABIN184770
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (5)
Cat. No.
ABIN7258158
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF
Validations
- (4)
Cat. No.
ABIN7265851
Quantity
100 μL
Datasheet
Datasheet
Recommended BAG3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6954056
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962016
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5652163
Quantity
96 tests
Datasheet
Datasheet
Recommended BAG3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1346366
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN667755
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505080
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our BAG3 products
: "Bcl-2-associated athanogene 3(BAG3) is associated with tumor cell proliferation, migration, invasion and chemoresistance in colorectal cancer." in: BMC cancer, Vol. 18, Issue 1, pp. 793, (2019) (PubMed).: "Familial Dilated Cardiomyopathy Caused by a Novel Frameshift in the BAG3 Gene." in: PLoS ONE, Vol. 11, Issue 7, pp. e0158730, (2016) (PubMed).
: "Modulation of BAG3 Expression and Proteasomal Activity by sAPPα Does Not Require Membrane-Tethered Holo-APP." in: Molecular neurobiology, (2015) (PubMed).
: "Expression and clinical role of chemoresponse-associated genes in ovarian serous carcinoma." in: Gynecologic oncology, Vol. 139, Issue 1, pp. 30-9, (2015) (PubMed).
: "Withaferin A Induces Cell Death Selectively in Androgen-Independent Prostate Cancer Cells but Not in Normal Fibroblast Cells." in: PLoS ONE, Vol. 10, Issue 7, pp. e0134137, (2015) (PubMed).
: "A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy. ..." in: Cell death & disease, Vol. 6, pp. e1948, (2015) (PubMed).
: "Dynein function and protein clearance changes in tumor cells induced by a Kunitz-type molecule, Amblyomin-X." in: PLoS ONE, Vol. 9, Issue 12, pp. e111907, (2014) (PubMed).
: "Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 10, pp. 2804-19, (2013) (PubMed).
: "Expression of Bcl-2 and the antiapoptotic BAG family proteins in ovarian cancer." in: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 21, Issue 6, pp. 518-24, (2013) (PubMed).
: "Characterization of squamous esophageal cells resistant to bile acids at acidic pH: implication for Barrett's esophagus pathogenesis." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 300, Issue 2, pp. G292-302, (2011) (PubMed).
Synonyms and alternative names related to BAG3
BCL2 associated athanogene 3 L homeolog (bag3.L), BCL2-associated athanogene 3 (bag3), BCL2 associated athanogene 3 (BAG3), BCL2 associated athanogene 3 (bag3), BCL-2-associated athanogene 3 (BAG3), BCL2-associated athanogene 3 (Bag3), Bcl2-associated athanogene 3 (Bag3), AA407278, ATBAG3, BAG-3, BAG3, bag3-A, BCL-2-associated athanogene 3, BIS, Bis, CAIR-1, MFM6, mg638, MGC53113, T28J14.160, T28J14_160, zgc:100859Protein level used designations for BAG3
- BCL2-associated athanogene 3
- BAG family molecular chaperone regulator 3
- BAG family molecular chaperone regulator 3-like
- BCL2-binding athanogene 3
- bcl-2-binding protein Bis
- docking protein CAIR-1
- BAG-3
- Bcl-2-binding protein Bis
- Bcl-2-interacting death suppressor
- bcl-2-associated athanogene 3
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