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BAG1 Products

(BCL2-Associated Athanogene (BAG1))

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The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010].

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Featured BAG1 Categories

BAG1 Antibodies

High quality antibodies with extensive validation data.

BAG1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended BAG1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (10)
Cat. No. ABIN560026
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (5)
Cat. No. ABIN560027
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN389451
Quantity 400 μL
Datasheet Datasheet

Recommended BAG1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6212946
Quantity 96 tests
Datasheet Datasheet

Recommended BAG1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1346360
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346358
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN935097
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our BAG1 products

Sharma, Maras, Das, Hussain, Mishra, Shasthry, Sharma, Weiss, Elkrief, Rautou, Gilgenkrantz, Lotersztajn, Paradis, de la Grange, Junot, Moreau, Sarin: "Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness." in: Scientific reports, Vol. 7, Issue 1, pp. 6816, (2017) (PubMed).

An, Li, Yao, Li, Wang, Sun, Li, Meng, Wang: "BAG3 directly stabilizes Hexokinase 2 mRNA and promotes aerobic glycolysis in pancreatic cancer cells." in: The Journal of cell biology, Vol. 216, Issue 12, pp. 4091-4105, (2017) (PubMed).

van der Zee, Ten Hagen, Hop, van Dekken, Dicheva, Seynhaeve, Koning, Eggermont, van Eijck: "Bcl-2 associated anthanogen-1 (Bag-1) expression and prognostic value in pancreatic head and periampullary cancer." in: European journal of cancer (Oxford, England : 1990), Vol. 49, Issue 2, pp. 323-8, (2013) (PubMed).

Aust, Pils, Polterauer, Horvat, Cacsire Castillo-Tong, Pils, Dudek, Schmid, Speiser, Reinthaller, Grimm: "Expression of Bcl-2 and the antiapoptotic BAG family proteins in ovarian cancer." in: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 21, Issue 6, pp. 518-24, (2013) (PubMed).

Chun, Gacad, Nguyen, Hewison, Adams: "Co-chaperone potentiation of vitamin D receptor-mediated transactivation: a role for Bcl2-associated athanogene-1 as an intracellular-binding protein for 1,25-dihydroxyvitamin D3." in: Journal of molecular endocrinology, Vol. 39, Issue 2, pp. 81-9, (2007) (PubMed).

Bai, Yi, Li, Sui: "Clinicopathologic significance of BAG1 and TIMP3 expression in colon carcinoma." in: World journal of gastroenterology, Vol. 13, Issue 28, pp. 3883-5, (2007) (PubMed).

Krajewska, Turner, Shabaik, Krajewski, Reed: "Expression of BAG-1 protein correlates with aggressive behavior of prostate cancers." in: The Prostate, Vol. 66, Issue 8, pp. 801-10, (2006) (PubMed).

Divanovic, Trompette, Atabani, Madan, Golenbock, Visintin, Finberg, Tarakhovsky, Vogel, Belkaid, Kurt-Jones, Karp: "Inhibition of TLR-4/MD-2 signaling by RP105/MD-1." in: Journal of endotoxin research, Vol. 11, Issue 6, pp. 363-8, (2005) (PubMed).

Nagai, Kobayashi, Motoi, Ishiguro, Akashi, Saitoh, Kusumoto, Kaisho, Akira, Matsumoto, Takatsu, Miyake: "The radioprotective 105/MD-1 complex links TLR2 and TLR4/MD-2 in antibody response to microbial membranes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7043-9, (2005) (PubMed).

Liman, Ganesan, Dohm, Krajewski, Reed, Bähr, Wouters, Kermer: "Interaction of BAG1 and Hsp70 mediates neuroprotectivity and increases chaperone activity." in: Molecular and cellular biology, Vol. 25, Issue 9, pp. 3715-25, (2005) (PubMed).

Synonyms and alternative names related to BAG1

BCL2 associated athanogene 1 (BAG1), putative bcl2-associated athanogene (Smp_005900), BCL2-associated athanogene 1 (Bag1), Bcl2 associated athanogene 1 (Bag1), BAG family molecular chaperone regulator 1 (bag-1), BCL-2-associated athanogene 1 (BAG1), BAG family molecular chaperone regulator 1 (LOC781741), BCL2-associated athanogene 1 (bag1), ATBAG1, BAG-1, Bag-1, BCL-2-associated athanogene 1, HAP, im:7148830, MSG15.15, MSG15_15, RAP46, Rap46, si:dkey-216e9.4

Protein level used designations for BAG1

  • BAG family molecular chaperone regulator 1
  • Bcl-2 associating athanogene-1 protein
  • Bcl-2-binding protein
  • glucocortoid receptor-associated protein RAP46
  • receptor-associated protein, 46-KD
  • bcl2-associated athanogene
  • BCL2-associated athanogene
  • bcl-2-associated athanogene 1
  • hydroxysteroid (17-beta) dehydrogenase 3
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