AXL Products
(AXL Receptor tyrosine Kinase (AXL))
Categories
The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Featured AXL Categories
AXL Antibodies
High quality antibodies with extensive validation data.
AXL ELISA Kits
Reliable ELISA kits for a wide range of species.
AXL Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AXL Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (1)
- (6)
Cat. No.
ABIN560017
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF
Validations
- (5)
Cat. No.
ABIN7265804
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (4)
Cat. No.
ABIN7265803
Quantity
100 μL
Datasheet
Datasheet
Recommended AXL ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954023
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954024
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN624944
Quantity
96 tests
Datasheet
Datasheet
Recommended AXL Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7273881
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7273880
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN6961128
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our AXL products
: "Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2. ..." in: Communications biology, Vol. 4, Issue 1, pp. 1002, (2021) (PubMed).: "Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5- and hypoxia- dependent up-regulation of AXL. ..." in: Haematologica, (2019) (PubMed).
: "Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors." in: Viruses, Vol. 11, Issue 3, (2019) (PubMed).
: "Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer." in: Cancer research, Vol. 79, Issue 10, pp. 2669-2683, (2019) (PubMed).
: "Inhibition of MERTK Promotes Suppression of Tumor Growth in BRAF Mutant and BRAF Wild-Type Melanoma." in: Molecular cancer therapeutics, Vol. 18, Issue 2, pp. 278-288, (2019) (PubMed).
: "p5RHH nanoparticle-mediated delivery of AXL siRNA inhibits metastasis of ovarian and uterine cancer cells in mouse xenografts." in: Scientific reports, Vol. 9, Issue 1, pp. 4762, (2019) (PubMed).
: "Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells." in: PLoS ONE, Vol. 14, Issue 5, pp. e0216275, (2019) (PubMed).
: "Lipopolysaccharide inhalation recruits monocytes and dendritic cell subsets to the alveolar airspace." in: Nature communications, Vol. 10, Issue 1, pp. 1999, (2019) (PubMed).
: "Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells." in: mBio, Vol. 10, Issue 4, (2019) (PubMed).
: "Platelets Promote Macrophage Polarization toward Pro-inflammatory Phenotype and Increase Survival of Septic Mice." in: Cell reports, Vol. 28, Issue 4, pp. 896-908.e5, (2019) (PubMed).
Synonyms and alternative names related to AXL
AXL receptor tyrosine kinase (AXL), AXL receptor tyrosine kinase (Axl), Axl receptor tyrosine kinase (Axl), AI323647, Ark, JTK11, Tyro7, UFO, UfoProtein level used designations for AXL
- AXL oncogene
- AXL transforming sequence/gene
- tyrosine-protein kinase receptor UFO
- adhesion-related kinase
- ufo oncogene homolog
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