AXIN2 Products
(Axin 2 (AXIN2))
Categories
The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair. [provided by RefSeq, Jul 2008].
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Featured AXIN2 Categories
AXIN2 Antibodies
High quality antibodies with extensive validation data.
AXIN2 ELISA Kits
Reliable ELISA kits for a wide range of species.
AXIN2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AXIN2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (4)
Cat. No.
ABIN6137382
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS
Validations
- (5)
Cat. No.
ABIN3030089
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA, IF
Validations
- (3)
Cat. No.
ABIN7139735
Quantity
100 μL
Datasheet
Datasheet
Recommended AXIN2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965100
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965099
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965098
Quantity
96 tests
Datasheet
Datasheet
Recommended AXIN2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121955
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346243
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346241
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our AXIN2 products
: "Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." in: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).Synonyms and alternative names related to AXIN2
axin 2 (AXIN2), axin 2 (conductin, axil) (axin2), axin 2 (conductin, axil) S homeolog (axin2.S), axin 2 (Axin2), arp-A, Axi1, AXIL, axil, Axil, axin-2, axin2, Conductin, MGC81576, ODCRCS, wu:fb37c08, xarp, zgc:111942Protein level used designations for AXIN2
- axin-2
- axin-like protein
- axis inhibition protein 2
- conductin
- etID37069.3
- axin 2 (conductin, axil)
- axin-related protein
- axin 2
- Axin-related protein
- axin-2-like
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