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Axin Proteins

(Axin 1 (AXIN1))

This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2010].

recommended

Axin Protein (AA 540-768) (His tag) (ABIN7121954)

AXIN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

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recommended

Axin Protein (AA 643-740) (GST tag) (ABIN1346237)

AXIN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

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recommended

Axin Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2715088)

AXIN1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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Axin Proteins by Origin

Find Axin Proteins for a variety of species such as anti-Human Axin, anti-Mouse Axin, anti-Rat Axin. The species listed below are among those available. Click on a link to go to the corresponding products.

Axin Proteins by Source

Here you will find Axin Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Axin Proteins by Protein Type

Here you can find Axin Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Axin Proteins by Application

Find Axin Proteins validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Axin Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Axin Protein (AA 540-768) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7121954

Quantity 50 μg

Datasheet Datasheet

Axin Protein (AA 643-740) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1346237

Quantity 10 μg

Datasheet Datasheet

Axin Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2715088

Quantity 20 μg

Datasheet Datasheet

Axin Protein (AA 654-863) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7405157

Quantity 100 μg

Datasheet Datasheet

Axin Protein (AA 653-862) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7406062

Quantity 100 μg

Datasheet Datasheet

Axin Protein (AA 618-827) (His tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7405900

Quantity 100 μg

Datasheet Datasheet

Axin Protein (AA 1-862) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3089641

Quantity 1 mg

Datasheet Datasheet

Axin Protein (AA 1-863) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3131624

Quantity 1 mg

Datasheet Datasheet

Axin Protein

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3008424

Quantity 100 μg

Datasheet Datasheet

Latest Publications for our Axin Proteins

Cha, Cho, Lee, Lee, Jeong, Moon, Yun, Yang, Choi, Yoon, Kim, Kim, Kaduwal, Lee, Min, Kim, Han, Choi: "Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation." in: Nature chemical biology, Vol. 12, Issue 8, pp. 593-600, (2016) (PubMed).

Aliases for Axin Proteins

axin 1 (AXIN1) Proteins
axin 1 S homeolog (axin1.S) Proteins
axin 1 L homeolog (axin1.L) Proteins
axin 1 (Axin1) Proteins
axin 1 (axin1) Proteins
AI316800 Proteins
axin Proteins
AXIN Proteins
Axin Proteins
AXIN1 Proteins
AXIN1-RGS Proteins
Fu Proteins
fused Proteins
Kb Proteins
Ki Proteins
kinky Proteins
knobbly Proteins
LOC100226467 Proteins
PPP1R49 Proteins
wu:fi22e03 Proteins
wu:fj14c08 Proteins
wu:fk11b03 Proteins
xAxin Proteins
zgc:109872 Proteins

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Axin Proteins by Origin

Axin Proteins by Source

Axin Proteins by Protein Type

Axin Proteins by Application

Popular Axin Proteins

Latest Publications for our Axin Proteins

Aliases for Axin Proteins

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