ATP7A Products
(ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))
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This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans-Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked cutis laxa, and occipital horn syndrome. [provided by RefSeq, Oct 2011].
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Featured ATP7A Categories
ATP7A Antibodies
High quality antibodies with extensive validation data.
ATP7A ELISA Kits
Reliable ELISA kits for a wide range of species.
ATP7A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ATP7A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF, ICC
Validations
- (4)
Cat. No.
ABIN2485193
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF, ICC
Validations
- (4)
Cat. No.
ABIN2485192
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF, ICC
Validations
- (4)
Cat. No.
ABIN2485191
Quantity
100 μg
Datasheet
Datasheet
Recommended ATP7A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965087
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1127849
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1127850
Quantity
96 tests
Datasheet
Datasheet
Recommended ATP7A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346155
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7423963
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7423960
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ATP7A products
: "miR-133a enhances the sensitivity of Hep-2 cells and vincristine-resistant Hep-2v cells to cisplatin by downregulating ATP7B expression." in: International journal of molecular medicine, Vol. 37, Issue 6, pp. 1636-42, (2016) (PubMed).: "Knockdown of copper-transporting ATPase 1 (Atp7a) impairs iron flux in fully-differentiated rat (IEC-6) and human (Caco-2) intestinal epithelial cells." in: Metallomics : integrated biometal science, Vol. 8, Issue 9, pp. 963-972, (2016) (PubMed).
: "Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 7, pp. 3381-8, (2015) (PubMed).
: "Copper transport into the secretory pathway is regulated by oxygen in macrophages." in: Journal of cell science, Vol. 122, Issue Pt 9, pp. 1315-21, (2009) (PubMed).
: "A role for the ATP7A copper-transporting ATPase in macrophage bactericidal activity." in: The Journal of biological chemistry, Vol. 284, Issue 49, pp. 33949-56, (2009) (PubMed).
: "Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes." in: Nature, Vol. 454, Issue 7208, pp. 1142-6, (2008) (PubMed).
: "Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 40, pp. 14919-24, (2006) (PubMed).
: "Menkes protein contributes to the function of peptidylglycine alpha-amidating monooxygenase." in: Endocrinology, Vol. 144, Issue 1, pp. 188-200, (2002) (PubMed).
Synonyms and alternative names related to ATP7A
ATPase copper transporting alpha (ATP7A), ATPase, Cu++ transporting, alpha polypeptide (ATP7A), ATPase, Cu++ transporting, alpha polypeptide (atp7a), P-type ATPase (atp7a), ATP synthase subunit a (LOC100049514), ATPase, Cu++ transporting, alpha polypeptide (Atp7a), ATPase copper transporting alpha (atp7a), copper-transporting ATPase 1 (LOC412379), ATPase copper transporting alpha (Atp7a), ATP7A, Atp7a, atp7a, atpase, Blo, blotchy, br, brindled, cal, DDBDRAFT_0218568, DDBDRAFT_0235190, DDB_0218568, DDB_0235190, DSMAX, DXHXS1608e, I14, kal, MK, MNK, Mnk, Mo, mottled, SMAX3, wu:fc43e01, zgc:153422, zgc:158633Protein level used designations for ATP7A
- ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome)
- ATPase, Cu++ transporting, alpha polypeptide
- Menkes disease ATPase
- calamity
- copper-transporting ATPase 1
- copper-transporting P-type ATPase
- copper-transporting ATPase
- ATPase protein
- kaleidoscope
- Copper-transporting ATPase 1
- copper-transporting ATPase 1-like
- Cu++-transporting P-type ATPase
- Menkes disease-associated protein
- copper pump 1
- Menkes protein
- menkes disease-associated protein homolog
- copper transporting ATPase
Did you look for something else?
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