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ATP6V1B2 Products

(ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

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This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008].

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Featured ATP6V1B2 Categories

ATP6V1B2 Antibodies

High quality antibodies with extensive validation data.

ATP6V1B2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ATP6V1B2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Chicken, Cow, Drosophila melanogaster, Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN1573989
Quantity 40 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN513630
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN560004
Quantity 100 μg
Datasheet Datasheet

Recommended ATP6V1B2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6201394
Quantity 96 tests
Datasheet Datasheet

Recommended ATP6V1B2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346119
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3075318
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2715056
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our ATP6V1B2 products

Sánchez-Mir, Franco, Martín-García, Madrid, Vicente-Soler, Soto, Gacto, Pérez, Cansado: "Rho2 palmitoylation is required for plasma membrane localization and proper signaling to the fission yeast cell integrity mitogen- activated protein kinase pathway." in: Molecular and cellular biology, Vol. 34, Issue 14, pp. 2745-59, (2014) (PubMed).

Eriksson, Joosten, Roberg, Ollinger: "The histone deacetylase inhibitor trichostatin A reduces lysosomal pH and enhances cisplatin-induced apoptosis." in: Experimental cell research, Vol. 319, Issue 1, pp. 12-20, (2012) (PubMed).

Ahmad, Khundmiri, Pribble, Merchant, Ameen, Klein, Levi, Lederer: "Role of vacuolar ATPase in the trafficking of renal type IIa sodium-phosphate cotransporter." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 27, Issue 6, pp. 703-14, (2011) (PubMed).

Nilsson, Roberg, Grafström, Ollinger: "Intrinsic differences in cisplatin sensitivity of head and neck cancer cell lines: Correlation to lysosomal pH." in: Head & neck, Vol. 32, Issue 9, pp. 1185-94, (2010) (PubMed).

Synonyms and alternative names related to ATP6V1B2

ATPase H+ transporting V1 subunit B2 (Atp6v1b2), ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 S homeolog (atp6v1b2.S), ATPase H+ transporting V1 subunit B2 (ATP6V1B2), ATPase, H+ transporting, lysosomal, V1 subunit B2 (atp6v1b2), ATPase, H+ transporting, lysosomal V1 subunit B2 (Atp6v1b2), AI194269, AI790362, Atp6b1b2, ATP6B1B2, Atp6b2, ATP6B2, atp6v1bb, fj51e01, HO57, R74844, Vatb, VATB, vatB2, vha55, Vma2, VPP3, wu:fj51e01, zgc:109771

Protein level used designations for ATP6V1B2

  • ATPase, H+ transporting, V1 subunit B
  • ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kDa
  • V-ATPase subunit B 2
  • V-type proton ATPase subunit B, brain isoform
  • endomembrane proton pump 58 kDa subunit
  • vacuolar H+ATPase B2
  • vacuolar proton pump subunit B 2
  • ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B
  • vacuolar H-ATPase B subunit osteoclast isozyme
  • H+ transporting two-sector ATPase
  • V-ATPase B2 subunit
  • vacuolar H+-ATPase 56,000 subunit
  • H+-ATPase B subunit
  • H+-ATPase non-catalytic subunit B
  • vacuolar H+-ATPase
  • Vacuolar ATP synthase subunit B, brain isoform
  • ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
  • ATPase, H+ transporting, lysosomal, V1 subunit B, member b
  • ATPase, H+ transporting, lysosomal 56/58kD, V1 subunit B
  • lysosomal 56/58kDa
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