ATP6V0B Products
(ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit B (ATP6V0B))
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This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the transmembrane V0 domain and is the human counterpart of yeast VMA16. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured ATP6V0B Categories
ATP6V0B Antibodies
High quality antibodies with extensive validation data.
Recommended ATP6V0B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN654391
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN513635
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN950566
Quantity
0.4 mL
Datasheet
Datasheet
Recommended ATP6V0B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3105720
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to ATP6V0B
ATPase H+ transporting V0 subunit b (ATP6V0B), ATPase, H+ transporting, lysosomal V0 subunit B (Atp6v0b), ATPase H+ transporting V0 subunit B (Atp6v0b), 2310024H13Rik, ATP6F, Atp6f, HATPL, VMA16Protein level used designations for ATP6V0B
- H(+)-transporting two-sector ATPase, subunit F
- V-ATPase 21 kDa proteolipid subunit
- V-ATPase subunit c''
- V-type proton ATPase 21 kDa proteolipid subunit
- vacuolar ATP synthase 21 kDa proteolipid subunit
- vacuolar proton pump 21 kDa proteolipid subunit
- vacuolar proton pump, 21 kDa subunit
- 23 kDa subunit of V-ATPase
- ATPase, H+ transporting, V0 subunit B
- ATPase, H+ transporting, lysosomal (vacuolar proton pump)
- ATPase, H+ transporting, lysosomal 21kDa, V0 subunit B
- lysosomal 21kDa
- ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
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