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ATP6V0A4 Products

(ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))

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This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing. [provided by RefSeq, Jul 2008].

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Featured ATP6V0A4 Categories

ATP6V0A4 Antibodies

High quality antibodies with extensive validation data.

ATP6V0A4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ATP6V0A4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN651562
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN1978851
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN2856797
Quantity 100 μL
Datasheet Datasheet

Recommended ATP6V0A4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3118247
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2715050
Quantity 20 μg
Datasheet Datasheet

Synonyms and alternative names related to ATP6V0A4

ATPase H+ transporting V0 subunit a4 (ATP6V0A4), ATPase, H+ transporting, lysosomal V0 subunit A4 (Atp6v0a4), A4, a4, ATP6N1B, Atp6n1b, ATP6N2, RDRTA2, RTA1C, RTADR, STV1, VPH1, VPP2

Protein level used designations for ATP6V0A4

  • ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 1B
  • ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 2 (38kD)
  • H(+)-transporting two-sector ATPase, noncatalytic accessory protein 1B
  • V-ATPase 116 kDa
  • V-type proton ATPase 116 kDa subunit a
  • V-type proton ATPase 116 kDa subunit a isoform 4
  • vacuolar proton pump 116 kDa accessory subunit
  • vacuolar proton pump, subunit 2
  • vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform
  • ATPase, H+ transporting, lysosomal (vacuolar proton pump) noncatalytic accessory protein 1B
  • V-ATPase alpha 4
  • vacuolar proton translocating ATPase 100 kDa a4 subunit
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