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ATP2C1 Products

(ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1))

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The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].

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Featured ATP2C1 Categories

ATP2C1 Antibodies

High quality antibodies with extensive validation data.

ATP2C1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ATP2C1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IF, IP, RNAi
Validations
  • (2)
  • (7)
Cat. No. ABIN565309
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey
Application ELISA, WB, IHC
Validations
  • (2)
  • (3)
Cat. No. ABIN1724719
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN3016170
Quantity 100 μL
Datasheet Datasheet

Recommended ATP2C1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5608518
Quantity 96 tests
Datasheet Datasheet

Recommended ATP2C1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346045
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7424224
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3114230
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ATP2C1 products

Chernyavsky, Amber, Agnoletti, Wang, Grando: "Synergy among non-desmoglein antibodies contributes to the immunopathology of desmoglein antibody-negative pemphigus vulgaris." in: The Journal of biological chemistry, Vol. 294, Issue 12, pp. 4520-4528, (2019) (PubMed).

Kienzle, Basnet, Crevenna, Beck, Habermann, Mizuno, von Blume: "Cofilin recruits F-actin to SPCA1 and promotes Ca2+-mediated secretory cargo sorting." in: The Journal of cell biology, Vol. 206, Issue 5, pp. 635-54, (2014) (PubMed).

Grice, Vetter, Faddy, Kenny, Roberts-Thomson, Monteith: "Golgi calcium pump secretory pathway calcium ATPase 1 (SPCA1) is a key regulator of insulin-like growth factor receptor (IGF1R) processing in the basal-like breast cancer cell line MDA-MB-231." in: The Journal of biological chemistry, Vol. 285, Issue 48, pp. 37458-66, (2010) (PubMed).

Pacheco-Rodriguez, Kumaki, Steagall, Zhang, Ikeda, Lin, Billings, Moss: "Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1270-7, (2009) (PubMed).

Yokota, Sawamura: "Hailey-Hailey disease with affective disorder: report of a case with novel ATP2C1 gene mutation." in: Journal of dermatological science, Vol. 43, Issue 2, pp. 150-1, (2006) (PubMed).

Majore, Biolcati, Barboni, Cannistraci, Binni, Crisi, Picardo, Grammatico: "ATP2C1 gene mutation analysis in Italian patients with Hailey-Hailey disease." in: The Journal of investigative dermatology, Vol. 125, Issue 5, pp. 933-5, (2005) (PubMed).

Synonyms and alternative names related to ATP2C1

ATPase secretory pathway Ca2+ transporting 1 (ATP2C1), ATPase, Ca++ transporting, type 2C, member 1 (ATP2C1), ATPase, Ca++ transporting, type 2C, member 1 (atp2c1), ATPase secretory pathway Ca2+ transporting 1 (Atp2c1), ATPase, Ca++-sequestering (Atp2c1), 1700121J11Rik, ATP2C1, ATP2C1A, AW061228, BCPM, D930003G21Rik, HHD, hSPCA1, PMR1, pmr1, si:dkey-11p23.6, SPCA, SPCA1, Spca1

Protein level used designations for ATP2C1

  • ATPase, Ca++ transporting, type 2C, member 1
  • ATPase 2C1
  • Calcium-transporting ATPase type 2C member 1
  • calcium-transporting ATPase type 2C member 1-like
  • ATP-dependent Ca(2+) pump PMR1
  • ATPase, Ca(2+)-sequestering
  • HUSSY-28
  • calcium-transporting ATPase type 2C member 1
  • secretory pathway Ca2+/Mn2+ ATPase 1
  • ATPase, Ca++-sequestering
  • calcium-transporting ATPase 2C1
  • secretory pathway Ca(2+)-ATPase 1
  • secretory pathway Ca(2+)-transporting ATPase
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