ATP2A1/SERCA1 Products
(ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1))
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This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured ATP2A1/SERCA1 Categories
ATP2A1/SERCA1 Antibodies
High quality antibodies with extensive validation data.
ATP2A1/SERCA1 ELISA Kits
Reliable ELISA kits for a wide range of species.
ATP2A1/SERCA1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ATP2A1/SERCA1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (6)
Cat. No.
ABIN559993
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
- (3)
Cat. No.
ABIN1881089
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
Cat. No.
ABIN5611123
Quantity
100 μL
Datasheet
Datasheet
Recommended ATP2A1/SERCA1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965083
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1156500
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1156502
Quantity
96 tests
Datasheet
Datasheet
Recommended ATP2A1/SERCA1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346035
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346033
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3109714
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ATP2A1/SERCA1 products
: "Atypical fast SERCA1a protein expression in slow myofibers and differential S-nitrosylation prevented by exercise during long term bed rest." in: Histochemistry and cell biology, Vol. 132, Issue 4, pp. 383-94, (2009) (PubMed).: "Role of SERCA1 truncated isoform in the proapoptotic calcium transfer from ER to mitochondria during ER stress." in: Molecular cell, Vol. 32, Issue 5, pp. 641-51, (2008) (PubMed).
: "Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity...." in: Nature genetics, Vol. 41, Issue 1, pp. 18-24, (2008) (PubMed).
: "Two Ca2+ ATPase genes: homologies and mechanistic implications of deduced amino acid sequences." in: Cell, Vol. 44, Issue 4, pp. 597-607, (1986) (PubMed).
Synonyms and alternative names related to ATP2A1/SERCA1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (atp2a1), ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 (ATP2A1), ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 S homeolog (atp2a2.S), ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (Atp2a1), ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 (Atp2a1), atp2a, ATP2A, ATP2A1, atp2a2, ATP2A3, atp2b, ca-p60a, cb279, dar, serca, serca1, SERCA1, Serca1, SERCA1a, serca2, wu:cegs655, wu:fb17h11, wu:fb19b10, zgc:92110Protein level used designations for ATP2A1/SERCA1
- ATPase, Ca++ transporting, fast twitch 1
- acc
- accordion
- sarcoendoplasmic reticulum calcium ATPase
- ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
- ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
- sarcoplasmic/endoplasmic reticulum calcium ATPase 1-like
- ATPase, Ca++ transporting, slow twitch 2
- sarcoplasmic/endoplasmic reticulum calcium ATPase 1
- ATPase, Ca++ transporting, ubiquitous
- SERCA1
- SR Ca(2+)-ATPase 1
- calcium pump 1
- calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform
- endoplasmic reticulum class 1/2 Ca(2+) ATPase
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