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ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Products

(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].

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Featured ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Categories

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antibodies

High quality antibodies with extensive validation data.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, FACS, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (4)
  • (4)
Cat. No. ABIN670161
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, FACS, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (1)
Cat. No. ABIN686977
Quantity 100 μL
Datasheet Datasheet
Reactivity Plasmodium falciparum
Application ELISA
Validations
Cat. No. ABIN7178310
Quantity 100 μg
Datasheet Datasheet

Recommended ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3132560
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5712796
Quantity 100 μg
Datasheet Datasheet
Reactivity Entamoeba histolytica
Source Yeast
Validations
  • (1)
Cat. No. ABIN5713190
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B products

Wei, Liang, Junsong, Rui, Shuai, Guanglin, Shicai, Zexing, Jin, Xiangming, Shufeng: "The impact of insulin on chemotherapeutic sensitivity to 5-fluorouracil in gastric cancer cell lines SGC7901, MKN45 and MKN28." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 64, (2016) (PubMed).

Sun, Jiao, Chen, Liu, Zhao: "MicroRNA-186 induces sensitivity of ovarian cancer cells to paclitaxel and cisplatin by targeting ABCB1." in: Journal of ovarian research, Vol. 8, pp. 80, (2016) (PubMed).

Liu, Zhou, Chen, Kang, Lu, Liu, Zang, Wang, Zhang: "Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice." in: Scientific reports, Vol. 5, pp. 13558, (2016) (PubMed).

Mo, Pospichalova, Huang, Murphy, Payne, Wang, Kennedy, Cianciolo, Bryja, Pizzo, Bachelder: "Ascites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells." in: PLoS ONE, Vol. 10, Issue 7, pp. e0131579, (2015) (PubMed).

Peng, Feng, Yuan, Benhabbour, Mumper: "Development of a novel orthotopic non-small cell lung cancer model and therapeutic benefit of 2'-(2-bromohexadecanoyl)-docetaxel conjugate nanoparticles." in: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1497-506, (2014) (PubMed).

Hu, Peng, Li: "The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 144, (2009) (PubMed).

Synonyms and alternative names related to ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B

ATP binding cassette subfamily B member 1 (ABCB1), ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b), ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b), ABC20, Abcb1, CD243, CLCS, GP170, mdr, MDR1, Mdr1, Mdr1b, P-GP, Pgy-1, PGY1, Pgy1

Protein level used designations for ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B

  • P-glycoprotein 1
  • colchicin sensitivity
  • doxorubicin resistance
  • multidrug resistance protein 1
  • ATP-binding cassette sub-family B member 1
  • P glycoprotein 1
  • multidrug resistance protein 1B
  • ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1)
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1)
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B
  • ATP-binding cassette, subfamily B, member 1B
  • P-glycoprotein/multidrug resistance 1
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