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ATG4B Products

(Autophagy related 4B Cysteine Peptidase (ATG4B))

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Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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Featured ATG4B Categories

ATG4B Antibodies

High quality antibodies with extensive validation data.

ATG4B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ATG4B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (2)
  • (4)
Cat. No. ABIN388494
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF
Validations
  • (6)
  • (4)
Cat. No. ABIN1882065
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (5)
Cat. No. ABIN7193464
Quantity 100 μL
Datasheet Datasheet

Recommended ATG4B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951529
Quantity 96 tests
Datasheet Datasheet

Recommended ATG4B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121952
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345972
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2128055
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ATG4B products

Andaloussi, Habib, Soylemes, Laknaur, Elhusseini, Al-Hendy, Ismail: "Defective expression of ATG4D abrogates autophagy and promotes growth in human uterine fibroids." in: Cell death discovery, Vol. 3, pp. 17041, (2018) (PubMed).

Li, Zhao, Wang, Shao, Wang, Wang, Xing: "Regulation of autophagy factors by oxidative stress and cardiac enzymes imbalance during arsenic or/and copper induced cardiotoxicity in Gallus gallus." in: Ecotoxicology and environmental safety, Vol. 148, pp. 125-134, (2018) (PubMed).

Sun, Li, Zhao, Wang, Liu, Shao, Xue, Xing: "Synergistic effect of copper and arsenic upon oxidative stress, inflammation and autophagy alterations in brain tissues of Gallus gallus." in: Journal of inorganic biochemistry, Vol. 178, pp. 54-62, (2018) (PubMed).

Shao, Zhao, Wang, Liu, Zong, Xing: "Copper-Mediated Mitochondrial Fission/Fusion Is Associated with Intrinsic Apoptosis and Autophagy in the Testis Tissues of Chicken." in: Biological trace element research, (2018) (PubMed).

Shao, Zhao, Wang, Liu, Li, Luo, Xing: "The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken." in: Poultry science, Vol. 97, Issue 9, pp. 3248-3257, (2018) (PubMed).

Yang, Zhao, Mei, Jiang, Geng, Li, Yao, Liu, Kong, Cao: "HMGA2 plays an important role in Cr (VI)-induced autophagy." in: International journal of cancer, Vol. 141, Issue 5, pp. 986-997, (2017) (PubMed).

Bhowmik, Gomes: "NKCT1 (purified Naja kaouthia protein toxin) conjugated gold nanoparticles induced Akt/mTOR inactivation mediated autophagic and caspase 3 activated apoptotic cell death in leukemic cell." in: Toxicon : official journal of the International Society on Toxinology, Vol. 121, pp. 86-97, (2016) (PubMed).

Armstrong, Mattsson, Appelqvist, Janefjord, Sandin, Agholme, Olsson, Svensson, Blennow, Zetterberg, Kågedal: "Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer's disease." in: Neuromolecular medicine, Vol. 16, Issue 1, pp. 150-60, (2014) (PubMed).

Li, Chen, Ye, Vogt, Yin: "A high-throughput FRET-based assay for determination of Atg4 activity." in: Autophagy, Vol. 8, Issue 3, pp. 401-12, (2012) (PubMed).

Okamoto, Sakimoto, Imai, Senoo, Shidoji: "Induction of an incomplete autophagic response by cancer-preventive geranylgeranoic acid (GGA) in a human hepatoma-derived cell line." in: The Biochemical journal, Vol. 440, Issue 1, pp. 63-71, (2011) (PubMed).

Synonyms and alternative names related to ATG4B

autophagy related 4B cysteine peptidase (ATG4B), autophagy-related 4b (Atg4b), Peptidase family C54 protein (AT3G59950), cysteine protease ATG4B (Tsp_08582), cysteine protease ATG4B (Tsp_11599), ATG4 autophagy related 4 homolog B (S. cerevisiae) (atg4b), autophagy related 4B, cysteine peptidase (atg4b), autophagy related 4B, cysteine peptidase L homeolog (atg4b.L), autophagy related 4B, cysteine peptidase (Atg4b), 2510009N07Rik, apg4b, APG4B, Apg4b, Atg4bl, Aut2b2, AUTL1, Autl1, AW048066

Protein level used designations for ATG4B

  • ATG4 autophagy related 4 homolog B
  • cysteine protease ATG4B
  • autophagy 4b variant 1Cysteine protease ATG4B
  • autophagy 4b variant 3
  • cysteine protease ATG4b
  • APG4 autophagy 4 homolog B
  • autophagy-related protein 4 homolog B
  • AUT2B
  • autophagin-2B
  • autophagy-related cysteine endopeptidase 2B
  • cAut2B
  • AUT-like 1 cysteine endopeptidase
  • autophagin-1
  • autophagy-related cysteine endopeptidase 1
  • hAPG4B
  • APG4 (ATG4) autophagy-related homolog B
  • AUT-like 1, cysteine endopeptidase
  • autophagin 1
  • autophagy-related 4B
  • cysteine protease involved in autophagy APG4-B
  • autophagy related 4 homolog B
  • autophagy related 4-like protein B
  • bAut2B
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