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ATG12 Products

(Autophagy Related 12 (ATG12))

Categories

Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008].

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Featured ATG12 Categories

ATG12 Antibodies

High quality antibodies with extensive validation data.

ATG12 ELISA Kits

Reliable ELISA kits for a wide range of species.

ATG12 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ATG12 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet

Application WB, IF
Validations
  • (1)
  • (7)
Cat. No. ABIN6254241
Quantity 600 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (5)
  • (4)
Cat. No. ABIN388536
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (7)
Cat. No. ABIN3028485
Quantity 0.4 mL
Datasheet Datasheet

Recommended ATG12 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965096
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954018
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954019
Quantity 96 tests
Datasheet Datasheet

Recommended ATG12 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345956
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345958
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3089416
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ATG12 products

Chang, Bijian, Wernic, Su, da Silva, Yu, Qiu, Asslan, Alaoui-Jamali: "A novel orally available seleno-purine molecule suppresses triple-negative breast cancer cell proliferation and progression to metastasis by inducing cytostatic autophagy." in: Autophagy, Vol. 15, Issue 8, pp. 1376-1390, (2019) (PubMed).

Tan, Zhou, Han, Hou, Kang, Zhang: "MicroRNA-378 enhances migration and invasion in cervical cancer by directly targeting autophagy-related protein 12." in: Molecular medicine reports, Vol. 17, Issue 5, pp. 6319-6326, (2018) (PubMed).

Bechor, Nachmias, Elia, Haim, Vatarescu, Leikin-Frenkel, Gericke, Tarnovscki, Las, Rudich: "Adipose tissue conditioned media support macrophage lipid-droplet biogenesis by interfering with autophagic flux." in: Biochimica et biophysica acta, Vol. 1862, Issue 9, pp. 1001-1012, (2017) (PubMed).

Chang, Bijian, Qiu, Su, Saad, Dahabieh, Miller, Alaoui-Jamali: "Endosomal sorting and c-Cbl targeting of paxillin to autophagosomes regulate cell-matrix adhesion turnover in human breast cancer cells." in: Oncotarget, Vol. 8, Issue 19, pp. 31199-31214, (2017) (PubMed).

Yang, Zhao, Mei, Jiang, Geng, Li, Yao, Liu, Kong, Cao: "HMGA2 plays an important role in Cr (VI)-induced autophagy." in: International journal of cancer, Vol. 141, Issue 5, pp. 986-997, (2017) (PubMed).

Kharaziha, Panaretakis: "Dynamics of Atg5-Atg12-Atg16L1 Aggregation and Deaggregation." in: Methods in enzymology, Vol. 587, pp. 247-255, (2017) (PubMed).

Bhowmik, Gomes: "NKCT1 (purified Naja kaouthia protein toxin) conjugated gold nanoparticles induced Akt/mTOR inactivation mediated autophagic and caspase 3 activated apoptotic cell death in leukemic cell." in: Toxicon : official journal of the International Society on Toxinology, Vol. 121, pp. 86-97, (2016) (PubMed).

Chen, Cao, Zhou, Liu, Che, Mizumura, Li, Choi, Shen: "Interaction of caveolin-1 with ATG12-ATG5 system suppresses autophagy in lung epithelial cells." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 11, pp. L1016-25, (2014) (PubMed).

Song, Kou, Zou, Gao, Zeng, Xie: "Involvement of autophagy in tri-ortho-cresyl phosphate- induced delayed neuropathy in hens." in: Neurochemistry international, Vol. 64, pp. 1-8, (2013) (PubMed).

Romanov, Walczak, Ibiricu, Schüchner, Ogris, Kraft, Martens: "Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation." in: The EMBO journal, Vol. 31, Issue 22, pp. 4304-17, (2012) (PubMed).

Synonyms and alternative names related to ATG12

autophagy related 12 (ATG12), autophagy related 12 (Atg12), Ubiquitin-like superfamily protein (APG12B), Atg12p (ATG12), autophagy protein (APG12), ubiquitin-like protein ATG12B (LOC9321066), autophagy associated protein Atg12 (apg12), Autophagy-related 12 (Atg12), ATG12 autophagy related 12 homolog (S. cerevisiae) (atg12), ATG12 autophagy related 12 homolog (S. cerevisiae) pseudogene (LOC743425), autophagy associated ubiquitin-like modifier Atg12 (atg12), hypothetical protein (CAALFM_C113950CA), Autophagy-related protein 12 (Autophagy-related ubiquitin-like modifier ATG12) (ATG12), autophagy protein 12 (atg12), autophagy related 12 S homeolog (atg12.S), autophagy-related protein 12 (ANI_1_922094), autophagy-related protein 12 (AOR_1_1064164), 4931423H11Rik, A330058M13Rik, AO090001000593, APG12, apg12, APG12L, Apg12l, atg12, ATG12, Atg12l, AUTOPHAGY 12, AUTOPHAGY 12 B, CG10861, DDBDRAFT_0185323, DDBDRAFT_0191412, DDB_0185323, DDB_0191412, Dmel\\CG10861, FBR93, HAPG12

Protein level used designations for ATG12

  • ATG12 autophagy related 12 homolog
  • Apg12 (autophagy, yeast) homolog
  • ubiquitin-like protein ATG12
  • autophagy-related 12
  • autophagy-related protein 12
  • autophagy protein
  • APG12/APG12B
  • autophagy associated protein Atg12
  • Autophagy-related protein 12
  • Atg12-PB
  • CG10861-PB
  • ATG12 autophagy related 12 homolog (S. cerevisiae)
  • potential preautophagosome nucleating protein Atg12
  • Autophagy-related protein 12 (Autophagy-related ubiquitin-like modifier ATG12)
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