ATF4 Products
(Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
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This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011].
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Featured ATF4 Categories
ATF4 Antibodies
High quality antibodies with extensive validation data.
ATF4 ELISA Kits
Reliable ELISA kits for a wide range of species.
ATF4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ATF4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (7)
Cat. No.
ABIN7433582
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (6)
Cat. No.
ABIN5542583
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
- (5)
Cat. No.
ABIN559979
Quantity
100 μg
Datasheet
Datasheet
Recommended ATF4 ELISA Kits
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Reactivity
Analytical Method
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Cat. No.
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Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964571
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964570
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962050
Quantity
96 tests
Datasheet
Datasheet
Recommended ATF4 Proteins
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Reactivity
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Validations
Cat. No.
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Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1345933
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121669
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121668
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our ATF4 products
: "Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization." in: Nature communications, Vol. 11, Issue 1, pp. 4254, (2020) (PubMed).: "Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate." in: Disease models & mechanisms, Vol. 12, Issue 6, (2019) (PubMed).
: "EndophilinA2 protects against angiotensin II-induced cardiac hypertrophy by inhibiting angiotensin II type 1 receptor trafficking in neonatal rat cardiomyocytes." in: Journal of cellular biochemistry, (2018) (PubMed).
: "Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury." in: Scientific reports, Vol. 8, Issue 1, pp. 408, (2018) (PubMed).
: "Selenoprotein S silencing triggers mouse hepatoma cells apoptosis and necrosis involving in intracellular calcium imbalance and ROS-mPTP-ATP." in: Biochimica et biophysica acta. General subjects, Vol. 1862, Issue 10, pp. 2113-2123, (2018) (PubMed).
: "Identification of ASB7 as ER stress responsive gene through a genome wide in silico screening for genes with ERSE." in: PLoS ONE, Vol. 13, Issue 4, pp. e0194310, (2018) (PubMed).
: "Activation of the Integrated Stress Response and Metabolic Dysfunction in a Murine Model of Sleep Apnea." in: American journal of respiratory cell and molecular biology, Vol. 57, Issue 4, pp. 477-486, (2017) (PubMed).
: "Downregulation of miR-384-5p attenuates rotenone-induced neurotoxicity in dopaminergic SH-SY5Y cells through inhibiting endoplasmic reticulum stress." in: American journal of physiology. Cell physiology, Vol. 310, Issue 9, pp. C755-63, (2016) (PubMed).
: "HOXB9 acts as a negative regulator of activated human T cells in response to amino acid deficiency." in: Immunology and cell biology, Vol. 94, Issue 6, pp. 612-7, (2016) (PubMed).
: "Glutathione S-Transferase P-Mediated Protein S-Glutathionylation of Resident Endoplasmic Reticulum Proteins Influences Sensitivity to Drug-Induced Unfolded Protein Response." in: Antioxidants & redox signaling, (2016) (PubMed).
Synonyms and alternative names related to ATF4
activating transcription factor 4 (ATF4), activating transcription factor 4 (atf4), activating transcription factor 4 (Atf4), activating transcription factor 4 L homeolog (atf4.L), activating transcription factor 4a (atf4a), activating transcription factor 4b (atf4b), activating transcription factor 4 S homeolog (atf4.S), atf-4, Atf-4, ATF4, atf4, atf4-a, atf4-b, ATF4-I, atf4-ii, C/ATF, CREB-2, creb-2, CREB2, creb2, sb:eu681, TAXREB67, taxreb67, TXREB, txreb, wu:fb08f07, wu:fj01c08, wu:fk30b04, zgc:85951, zgc:171702Protein level used designations for ATF4
- DNA-binding protein TAXREB67
- cAMP response element-binding protein 2
- cAMP-dependent transcription factor ATF-4
- cAMP-responsive element-binding protein 2
- cyclic AMP-dependent transcription factor ATF-4
- cyclic AMP-responsive element-binding protein 2
- tax-responsive enhancer element B67
- tax-responsive enhancer element-binding protein 67
- activating transcription factor 4 (tax-responsive enhancer element B67)
- activating transcription factor ATF-4
- rATF-4
- activating transcription factor 4
- c/EBP-related ATF
- tax-responsive enhancer element-binding protein 67 homolog
- taxREB67 homolog
- Activating Transcription Factor 4 -I
- Activating Transcription Factor 4 -II
- activating transcription factor 4 S homeolog
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