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ATF2 Products

(Activating Transcription Factor 2 (ATF2))

Categories

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro\; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].

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Featured ATF2 Categories

ATF2 Antibodies

High quality antibodies with extensive validation data.

ATF2 ELISA Kits

Reliable ELISA kits for a wide range of species.

ATF2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ATF2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (7)
Cat. No. ABIN3023064
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IP, IF, ICC
Validations
  • (11)
Cat. No. ABIN6256594
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IP, IF, ICC
Validations
  • (5)
Cat. No. ABIN6255342
Quantity 100 μL
Datasheet Datasheet

Recommended ATF2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964567
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964566
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (2)
Cat. No. ABIN4886273
Quantity 96 tests
Datasheet Datasheet

Recommended ATF2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345925
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345927
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345923
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our ATF2 products

Zhang, He, Wang, Zhang, Huang, Xiong, Yan, Wu, Ren, Han, Liu, Qian, Du: "Virus-Triggered ATP Release Limits Viral Replication through Facilitating IFN-β Production in a P2X7-Dependent Manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 4, pp. 1372-1381, (2017) (PubMed).

Zhang, Pan, Xu, Niu, Ma, Xu: "Interleukin 18 augments growth ability via NF-?B and p38/ATF2 pathways by targeting cyclin B1, cyclin B2, cyclin A2, and Bcl-2 in BRL-3A rat liver cells." in: Gene, Vol. 563, Issue 1, pp. 45-51, (2015) (PubMed).

Jindal, Mahesh, Bhatt et al.: "Etazolate, a phosphodiesterase-4 enzyme inhibitor produces antidepressant-like effects by blocking the behavioral, biochemical, neurobiological deficits and histological abnormalities in hippocampus ..." in: Psychopharmacology, Vol. 232, Issue 3, pp. 623-37, (2015) (PubMed).

Bengoa-Vergniory, Gorroño-Etxebarria, González-Salazar, Kypta: "A switch from canonical to noncanonical Wnt signaling mediates early differentiation of human neural stem cells." in: Stem cells (Dayton, Ohio), Vol. 32, Issue 12, pp. 3196-208, (2014) (PubMed).

Muñoz, Kawahara, Yannone: "An autonomous chromatin/DNA-PK mechanism for localized DNA damage signaling in mammalian cells." in: Nucleic acids research, Vol. 41, Issue 5, pp. 2894-906, (2013) (PubMed).

Wang, Saha, Hada, Anderson, Pluth, ONeill, Cucinotta: "Novel Smad proteins localize to IR-induced double-strand breaks: interplay between TGFβ and ATM pathways." in: Nucleic acids research, Vol. 41, Issue 2, pp. 933-42, (2013) (PubMed).

Chappell, Whalen, Gurai, Ponomarev, Cucinotta, Pluth: "Analysis of Flow Cytometry DNA Damage Response Protein Activation Kinetics after Exposure to X Rays and High-Energy Iron Nuclei." in: Radiation research, (2010) (PubMed).

Chen, Takeuchi, Moroi, Hayashida, Kido, Chen, Tomoeda, Uenotsuchi, Tu, Furue, Urabe: "Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous squamous cell carcinoma, Bowen's disease and basal cell carcinoma." in: Journal of dermatological science, Vol. 51, Issue 3, pp. 210-5, (2008) (PubMed).

Bhoumik, Singha, OConnell, Ronai: "Regulation of TIP60 by ATF2 modulates ATM activation." in: The Journal of biological chemistry, Vol. 283, Issue 25, pp. 17605-14, (2008) (PubMed).

Sevilla, Santos, Vega, Lazo: "Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK." in: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27458-65, (2004) (PubMed).

Synonyms and alternative names related to ATF2

activating transcription factor 2 (ATF2), Activating transcription factor-2 (Atf-2), activating transcription factor 2 (Atf2), activating transcription factor 2 S homeolog (atf2.S), activating transcription factor 2 (atf2), Atf-2, atf2-A, atf2l, CG3749, CG12850, CG30420, CHN1, CRE-BP, CRE-BP1, CREB2, Creb2, D18875, D130078H02Rik, dATF-2, DmelCG30420, HB16, mXBP, Tg(Gzma-Klra1)7Wum, TREB7

Protein level used designations for ATF2

  • CREB-2
  • activating transcription factor 2 splice variant ATF2-var2
  • cAMP response element-binding protein CRE-BP1
  • cAMP responsive element binding protein 2, formerly
  • cAMP-dependent transcription factor ATF-2
  • cAMP-responsive element-binding protein 2
  • cyclic AMP-dependent transcription factor ATF-2
  • cyclic AMP-responsive element-binding protein 2
  • activating transcription factor-2, isoform A
  • CG30420-PA
  • Atf-2-PA
  • activating transcription factor-2, isoform C
  • CG30420-PC
  • Atf-2-PC
  • activating transcription factor-2, isoform B
  • CG30420-PB
  • Atf-2-PB
  • cyclic AMP response element binding protein 2
  • chimerin (chimaerin) 1
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