Ataxin 3 Products
(Ataxin 3 (ATXN3))
Categories
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2009].
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Featured Ataxin 3 Categories
Ataxin 3 Antibodies
High quality antibodies with extensive validation data.
Ataxin 3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Ataxin 3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (9)
Cat. No.
ABIN3021829
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (4)
Cat. No.
ABIN653191
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IP
Validations
- (1)
- (3)
Cat. No.
ABIN2856981
Quantity
100 μL
Datasheet
Datasheet
Recommended Ataxin 3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Sandwich ELISA
Validations
Cat. No.
ABIN418941
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6201829
Quantity
96 tests
Datasheet
Datasheet
Recommended Ataxin 3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346195
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346197
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN935045
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our Ataxin 3 products
: "The Truncated C-terminal Fragment of Mutant ATXN3 Disrupts Mitochondria Dynamics in Spinocerebellar Ataxia Type 3 Models." in: Frontiers in molecular neuroscience, Vol. 10, pp. 196, (2017) (PubMed).: "Ataxin-3 expression correlates with the clinicopathologic features of gastric cancer." in: International journal of clinical and experimental medicine, Vol. 7, Issue 4, pp. 973-81, (2014) (PubMed).
: "Molecular architecture of CAG repeats in human disease related transcripts." in: Journal of molecular biology, Vol. 340, Issue 4, pp. 665-79, (2004) (PubMed).
: "Sequence-dependent and independent inhibition specific for mutant ataxin-3 by small interfering RNA." in: Annals of neurology, Vol. 56, Issue 1, pp. 124-9, (2004) (PubMed).
: "Structural and functional analysis of ataxin-2 and ataxin-3." in: European journal of biochemistry / FEBS, Vol. 271, Issue 15, pp. 3155-70, (2004) (PubMed).
: "The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 19, pp. 10116-21, (1997) (PubMed).
: "Machado-Joseph disease gene product is a cytoplasmic protein widely expressed in brain." in: Annals of neurology, Vol. 41, Issue 4, pp. 453-62, (1997) (PubMed).
Synonyms and alternative names related to Ataxin 3
ataxin 3 (atxn3), ataxin 3 (ATXN3), ataxin 3 L homeolog (atxn3.L), ataxin-3 (MICPUN_104046), ataxin-3 (MICPUCDRAFT_46658), ataxin 3 (Atxn3), 2210008M02Rik, AI463012, AI647473, at3, AT3, ataxin-3, atx3, ATX3, ATXN3, jos, JOS, MGC83584, Mjd, mjd, MJD, mjd1, MJD1, Rsca3, sca3, SCA3, Sca3, zgc:56323Protein level used designations for Ataxin 3
- ataxin-3
- ataxin 3
- ataxin-3-like
- Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3)
- Machado-Joseph disease protein 1
- ataxin 3 variant h
- ataxin 3 variant m
- ataxin 3 variant ref
- josephin
- olivopontocerebellar ataxia 3
- spinocerebellar ataxia type 3 protein
- Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) homolog
- machado-Joseph disease protein 1 homolog
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