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Ataxin 1 Proteins

(Ataxin 1 (ATXN1))

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2010].

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Ataxin 1 Protein (ATXN1) (AA 576-675) (GST tag) (ABIN1346189)

ATXN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

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ATXN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC

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ATXN1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC

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Ataxin 1 Proteins by Origin

Find Ataxin 1 Proteins for a variety of species such as anti-Human Ataxin 1, anti-Mouse Ataxin 1. The species listed below are among those available. Click on a link to go to the corresponding products.

Ataxin 1 Proteins by Source

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Ataxin 1 Proteins by Protein Type

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Ataxin 1 Proteins by Application

Find Ataxin 1 Proteins validated for a specific application such as WB, SDS, ELISA, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Ataxin 1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Ataxin 1 Protein (ATXN1) (AA 576-675) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1346189

Quantity 10 μg

Datasheet Datasheet

Ataxin 1 Protein (ATXN1) (AA 569-807) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7390679

Quantity 100 μg

Datasheet Datasheet

Ataxin 1 Protein (ATXN1) (AA 331-587) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7415551

Quantity 100 μg

Datasheet Datasheet

Ataxin 1 Protein (ATXN1) (AA 1-815) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3089722

Quantity 1 mg

Datasheet Datasheet

Ataxin 1 Protein (ATXN1) (AA 1-791) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3119805

Quantity 1 mg

Datasheet Datasheet

Ataxin 1 Protein (ATXN1) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2715013

Quantity 20 μg

Datasheet Datasheet

Ataxin 1 Protein (ATXN1) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2715012

Quantity 20 μg

Datasheet Datasheet

Latest Publications for our Ataxin 1 Proteins

Yoon, Abdelmohsen, Kim, Yang, Martindale, Tominaga-Yamanaka, White, Orjalo, Rinn, Kreft, Wilson, Gorospe: "Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination." in: Nature communications, Vol. 4, pp. 2939, (2013) (PubMed).

Aliases for Ataxin 1 Proteins

ataxin 1 (ATXN1) Proteins
ataxin 1b (atxn1b) Proteins
ataxin 1 (Atxn1) Proteins
Ataxin 1 (Atx-1) Proteins
2900016G23Rik Proteins
ataxin 1b Proteins
ATX1 Proteins
Atx1 Proteins
ATXN1 Proteins
atxn1 Proteins
C85907 Proteins
CG4547 Proteins
D6S504E Proteins
dAtx-1 Proteins
dAtx1 Proteins
Dmel\\CG4547 Proteins
ENSMUSG00000074917 Proteins
Gm10786 Proteins
SCA1 Proteins
Sca1 Proteins
sca1 Proteins

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Ataxin 1 Proteins by Origin

Ataxin 1 Proteins by Source

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Ataxin 1 Proteins by Application

Popular Ataxin 1 Proteins

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Aliases for Ataxin 1 Proteins

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