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ASNA1 Products

(ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1))

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This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion. [provided by RefSeq, Oct 2011].

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Featured ASNA1 Categories

ASNA1 Antibodies

High quality antibodies with extensive validation data.

ASNA1 ELISA Kits

Reliable ELISA kits for a wide range of species.

ASNA1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ASNA1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p), RNAi
Validations
  • (3)
  • (8)
Cat. No. ABIN559968
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (4)
Cat. No. ABIN2856957
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN1678763
Quantity 100 μg
Datasheet Datasheet

Recommended ASNA1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1123011
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1123012
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1123010
Quantity 96 tests
Datasheet Datasheet

Recommended ASNA1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345866
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN1098415
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345865
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our ASNA1 products

Ott, Marques, Funk, Bailer: "Asna1/TRC40 that mediates membrane insertion of tail-anchored proteins is required for efficient release of Herpes simplex virus 1 virions." in: Virology journal, Vol. 13, Issue 1, pp. 175, (2016) (PubMed).

Baron, Pedrioli, Tyagi, Johnson, Wood, Fountaine, Wightman, Alexandru: "VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase." in: BMC biology, Vol. 12, pp. 39, (2014) (PubMed).

Kim, Yun, Lee, Jeong, Baek, Song, Ju, Youdim, Jin, Kim, Oh: "Gel-based protease proteomics for identifying the novel calpain substrates in dopaminergic neuronal cell." in: The Journal of biological chemistry, Vol. 288, Issue 51, pp. 36717-32, (2013) (PubMed).

Rabu, Wipf, Brodsky, High: "A precursor-specific role for Hsp40/Hsc70 during tail-anchored protein integration at the endoplasmic reticulum." in: The Journal of biological chemistry, Vol. 283, Issue 41, pp. 27504-13, (2008) (PubMed).

Hemmingsson, Zhang, Still, Naredi: "ASNA1, an ATPase targeting tail-anchored proteins, regulates melanoma cell growth and sensitivity to cisplatin and arsenite." in: Cancer chemotherapy and pharmacology, Vol. 63, Issue 3, pp. 491-9, (2008) (PubMed).

Kao, Nordenson, Still, Rönnlund, Tuck, Naredi: "ASNA-1 positively regulates insulin secretion in C. elegans and mammalian cells." in: Cell, Vol. 128, Issue 3, pp. 577-87, (2007) (PubMed).

Ordentlich, Downes, Xie, Genin, Spinner, Evans: "Unique forms of human and mouse nuclear receptor corepressor SMRT." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 6, pp. 2639-44, (1999) (PubMed).

Wagner, Norris, Knotts, Weigel, McDonnell: "The nuclear corepressors NCoR and SMRT are key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor." in: Molecular and cellular biology, Vol. 18, Issue 3, pp. 1369-78, (1998) (PubMed).

Nagy, Kao, Chakravarti, Lin, Hassig, Ayer, Schreiber, Evans: "Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase." in: Cell, Vol. 89, Issue 3, pp. 373-80, (1997) (PubMed).

Chen, Evans: "A transcriptional co-repressor that interacts with nuclear hormone receptors." in: Nature, Vol. 377, Issue 6548, pp. 454-7, (1995) (PubMed).

Synonyms and alternative names related to ASNA1

arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) (ASNA1), arsenical pump-driving ATPase (ATEG_04670), arsenical pump-driving ATPase (arsA2), pseudo (arsA), arsenical pump-driving ATPase (HCAG_00048), ATPase ASNA1 homolog (LOC5574421), arsenical pump-driving ATPase (CC1G_08655), arsenical pump-driving ATPase (CpipJ_CPIJ005690), arsenical pump-driving ATPase (PTRG_02265), arsenite-translocating ATPase; arsenical resistance ATPase; arsenite-transporting ATPase (pKlebpneu12_p77), arsenical pump-driving ATPase (UREG_07455), arsenical pump-driving ATPase (BDBG_06308), arsenical pump-driving ATPase (MCYG_00630), arsenical pump-driving ATPase (LOC100284977), arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) (Asna1), arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) (asna1), arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) S homeolog (asna1.S), arsenical pump-driving ATPase (MGYG_01332), L-asparaginase (asnA1), arsenical pump-driving ATPase (Tsp_06776), ATPase asna-1 (asna-1), 1810048H22Rik, ArsA, ARSA-I, arsa-i, ARSA1, arsa1, ASNA-I, ASNA1, asna1, GET3, hASNA-I, MGC146316, TRC40, wu:fd05d03, zgc:56540, zgc:86799

Protein level used designations for ASNA1

  • ATPase ASNA1
  • arsenical pump-driving ATPase
  • arsenite-stimulated ATPase
  • golgi to ER traffic 3 homolog
  • transmembrane domain recognition complex 40 kDa ATPase subunit
  • transmembrane domain recognition complex, 40kDa
  • arsenical pump-driving atpase
  • ATPase Asna1
  • arsenite-translocating ATPase
  • arsA arsenite transporter, ATP-binding, homolog 1
  • ATPase asna1
  • arsenical resistance ATPase
  • arsenite-transporting ATPase
  • arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
  • Arsenical pump-driving ATPase
  • Arsenical resistance ATPase
  • Arsenite-translocating ATPase
  • Arsenite-transporting ATPase
  • arsA arsenite transporter, ATP-binding homolog 1
  • ATPase ASNA1-like
  • L-asparaginase
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