ASAP1 Products
(ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))
Categories
This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
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Featured ASAP1 Categories
ASAP1 Antibodies
High quality antibodies with extensive validation data.
ASAP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
ASAP1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ASAP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
Cat. No.
ABIN565496
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN753703
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IHC
Validations
- (1)
- (1)
Cat. No.
ABIN129669
Quantity
100 μg
Datasheet
Datasheet
Recommended ASAP1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971241
Quantity
96 tests
Datasheet
Datasheet
Recommended ASAP1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345785
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3089560
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3137365
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ASAP1 products
: "Loss of ASAP1 in mice impairs adipogenic and osteogenic differentiation of mesenchymal progenitor cells through dysregulation of FAK/Src and AKT signaling." in: PLoS genetics, Vol. 15, Issue 6, pp. e1008216, (2019) (PubMed).: "Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect." in: Nature communications, Vol. 5, pp. 4746, (2015) (PubMed).
: "Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide." in: PLoS ONE, Vol. 8, Issue 10, pp. e77288, (2013) (PubMed).
: "Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEF." in: The Journal of biological chemistry, Vol. 283, Issue 47, pp. 33006-20, (2008) (PubMed).
: "Mislocalization or reduced expression of Arf GTPase-activating protein ASAP1 inhibits cell spreading and migration by influencing Arf1 GTPase cycling." in: The Journal of biological chemistry, Vol. 280, Issue 10, pp. 8884-92, (2005) (PubMed).
: "The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1." in: The Journal of biological chemistry, Vol. 278, Issue 32, pp. 29560-70, (2003) (PubMed).
: "The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly." in: Molecular biology of the cell, Vol. 13, Issue 6, pp. 2147-56, (2002) (PubMed).
Synonyms and alternative names related to ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain1 (Asap1), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ASAP1), toxic extracellular endopeptidase (asaP1), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (Asap1), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (asap1), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 L homeolog (asap1.L), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a (asap1a), AMAP1, ASAP1, Asap1, AV239055, CENTB4, Ddef1, DDEF1, ddef1, DEF-1, mKIAA1249, PAG2, PAP, s19, si:ch211-160i2.3, ZG14PProtein level used designations for ASAP1
- 130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein
- 130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein
- ADP-ribosylation factor-directed GTPase-activating protein 1
- ARF GTPase-activating protein 1
- PIP2-dependent ARF1 GAP
- arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
- development and differentiation-enhancing factor 1
- DEF-1
- centaurin, beta 4
- development and differentiation enhancing factor 1
- differentiation-enhancing factor 1
- ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
- arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1-like
- ArfGAP with SH3 domain, ankyrin repeat and PH domain1
- ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
- arfGAP with SH3 domain, ankyrin repeat and PH domain 1a
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