ASAH2 Products
(N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
Categories
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM, Mar 2008].
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Featured ASAH2 Categories
ASAH2 Antibodies
High quality antibodies with extensive validation data.
ASAH2 ELISA Kits
Reliable ELISA kits for a wide range of species.
ASAH2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ASAH2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7161486
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (3)
Cat. No.
ABIN7264037
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN604683
Quantity
0.05 mg
Datasheet
Datasheet
Recommended ASAH2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958013
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4881900
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730406
Quantity
96 tests
Datasheet
Datasheet
Recommended ASAH2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7197085
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7415830
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN6124928
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our ASAH2 products
: "Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha." in: The Journal of biological chemistry, Vol. 280, Issue 30, pp. 27879-87, (2005) (PubMed).: "O-glycosylation of mucin-like domain retains the neutral ceramidase on the plasma membranes as a type II integral membrane protein." in: The Journal of biological chemistry, Vol. 278, Issue 12, pp. 10523-30, (2003) (PubMed).
: "Alkaline sphingomyelinases and ceramidases of the gastrointestinal tract." in: Chemistry and physics of lipids, Vol. 102, Issue 1-2, pp. 97-105, (2000) (PubMed).
Synonyms and alternative names related to ASAH2
N-acylsphingosine amidohydrolase 2 (ASAH2), N-acylsphingosine amidohydrolase 2 (Asah2), AI585898, BCDase, HNAC1, LCDase, N-CDase, NCDaseProtein level used designations for ASAH2
- N-acylsphingosine amidohydrolase 2
- acylsphingosine deacylase 2
- mitochondrial ceramidase
- neutral ceramidase
- neutral/alkaline ceramidase
- non-lysosomal ceramidase
- N-CDase
- NCDase
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