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Endoderm Markers

In stem cell culture, the endoderm represents one of the three primary germ layers critical in embryonic development. It gives rise to various internal organs such as the liver, pancreas, and gastrointestinal tract. Controlling endodermal differentiation is essential in stem cell research for directing cells toward specific endodermal lineages, providing opportunities for regenerative medicine and disease modeling.

Endoderm antibody markers play a crucial role in identifying and characterizing endoderm-derived cell populations during stem cell differentiation. Prominent markers include FOXA2, SOX17, and GATA4, which are widely utilized to label and study cells committed to endodermal lineages. These antibodies enable researchers to monitor the progression of endodermal differentiation, ensuring the generation of specific cell types for therapeutic applications and advancing our understanding of organ development and function.

Endoderm Markers

Product
Reactivity
Clone
Application
Validations
Cat. No.
Quantity
Reactivity Human, Mouse, Rat
Clone
Application WB, ELISA, IHC, IF, ICC
Validations
  • (14)
Cat. No. ABIN6256227
Quantity 100 μL
Reactivity Dog, Human
Clone 2B6
Application WB, IHC, IF, IHC (p)
Validations
  • (6)
Cat. No. ABIN1491032
Quantity 100 μL
Reactivity Human, Rat
Clone
Application WB, ELISA, IHC
Validations
  • (1)
  • (4)
Cat. No. ABIN185022
Quantity 100 μg

The endoderm gives rise to a variety of internal organs and tissues including the epithelial lining of the gastrointestinal tract, which encompasses the stomach, small intestine, and large intestine. Endoderm also contributes to the formation of the liver, pancreas, and lungs. Additionally, structures such as the thyroid, parathyroid, and thymus originate from endodermal tissue. The diverse range of tissues and organs derived from the endoderm underscores its critical role in the development of the body's internal systems and functions.

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