Langerhans cells, specialized antigen-presenting cells in the skin and mucosal tissues, can be identified and characterized using specific antibody markers. The most prominent marker for Langerhans cells is CD1a, a surface marker involved in antigen presentation. Additionally, Langerin (CD207) is a unique marker expressed by Langerhans cells that plays a crucial role in their function. These markers facilitate the identification and study of Langerhans cells in various immunological and dermatological research, shedding light on their role in immune responses and skin disorders.